Tejwani Samir G, Hame Sharon L, Eckardt Jeffrey J
Department of Orthopaedic Surgery, University of California, Los Angeles School of Medicine, Los Angeles, California 90095, USA.
Arthroscopy. 2004 Jul;20(6):644-9. doi: 10.1016/j.arthro.2004.03.015.
Giant-cell tumor most commonly occurs in the distal femur and proximal tibia and characteristically involves the subchondral bone. Incomplete resection leads to recurrence rates of up to 50%. Intralesional curettage, adjuvant treatments, and polymethyl methacralate (PMMA) reconstruction is the current mainstay of treatment and has produced recurrence rates of less than 10%. Achieving adequate curettage while preserving the articular cartilage of the tibial plateau poses a significant challenge, especially when the tumor involves the subchondral bone. We report on 2 cases, both with symptomatic full-thickness tibial articular cartilage loss and one with a meniscal tear, after curettage, phenol cautery, and PMMA reconstruction of giant-cell tumor of the proximal tibia. Arthroscopic chondroplasty and planing of the exposed cement was performed in both cases, theoretically reducing focal areas of stress concentration that could lead to further meniscal damage and injury to the femoral condyle articular surface in weight-bearing. Partial meniscectomy for a complex meniscal tear was performed in one case. Eighteen months postoperatively, both patients were asymptomatic, working full-time, and participating in light physical activity. Repetitive heavy loading of the knee, such as running, was prohibited, and long-term follow-up is warranted to assess for further joint degeneration and need for total knee arthroplasty.
骨巨细胞瘤最常发生于股骨远端和胫骨近端,其特征是累及软骨下骨。不完全切除会导致高达50%的复发率。病灶内刮除、辅助治疗以及聚甲基丙烯酸甲酯(PMMA)重建是目前的主要治疗方法,复发率已低于10%。在保留胫骨平台关节软骨的同时实现充分刮除是一项重大挑战,尤其是当肿瘤累及软骨下骨时。我们报告2例胫骨近端骨巨细胞瘤经刮除、苯酚烧灼和PMMA重建后出现症状性全层胫骨关节软骨缺失的病例,其中1例伴有半月板撕裂。2例均进行了关节镜下软骨成形术以及对暴露骨水泥的修整,理论上可减少可能导致负重时半月板进一步损伤和股骨髁关节面损伤的应力集中局部区域。1例对复杂半月板撕裂进行了部分半月板切除术。术后18个月,2例患者均无症状,全职工作,并参与轻度体育活动。禁止对膝关节进行重复性重负荷运动,如跑步,需要进行长期随访以评估是否会出现进一步的关节退变以及是否需要进行全膝关节置换术。