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影响胸腰段移行区爆裂骨折后生活质量的因素。

Factors influencing the quality of life after burst fractures of the thoracolumbar transition.

作者信息

Briem D, Lehmann W, Ruecker A H, Windolf J, Rueger J M, Linhart W

机构信息

School of Medicine, Department of Trauma, Hand and Reconstructive Surgery, Hamburg University, Martinistr. 52, 20246 Hamburg, Germany.

出版信息

Arch Orthop Trauma Surg. 2004 Sep;124(7):461-8. doi: 10.1007/s00402-004-0710-5. Epub 2004 Jul 9.

Abstract

INTRODUCTION

Dorsal stabilisation has represented the standard procedure for the treatment of burst fractures of the thoracolumbar spine for a long time, but in the last few years the combined dorsoventral stabilisation has gained in significance due to its higher mechanical stability. However, there are no data yet available indicating whether the patients benefit from the combined operation with regard to their postoperative quality of life and what the advantages are in comparison with the dorsal procedures. Therefore, the question was researched in the framework of a matched-pairs analysis of patients suffering from an unstable fracture of the thoracolumbar transition.

MATERIALS AND METHODS

From a consecutive series of patients treated in our clinic between 1995 and 2000, 10 patients with combined and 10 patients with a purely dorsal stabilisation were selected and included in the study. Their quality of life was summed up in retrospect with the SF-36 questionnaire. The X-rays were analysed, and the Cobb angle as well as the sagittal index were calculated. Only patients with burst fractures of the thoracolumbar transition without accompanying co-morbidity and neurological deficits were included in the study. Both of the treated groups were matched with regard to sex, age and radiological patterns of injury.

RESULTS

Patients who had undergone only a dorsal stabilisation showed a significant loss of correction according to the sagittal index at the time of the examination (0.88+/-0.02 postoperative vs 0.77+/-0.03 at 4 years postoperatively, p=0.01). In the group of patients treated with the combined therapy, there was no statistically relevant loss of correction with regard to the sagittal vertebral profile. The SF-36 questionnaire showed a reduced quality of life in both groups compared with an age-referenced norm population, especially concerning the parameters of bodily health. No statistically relevant difference was observed between the two groups. Further, there was no statistically relevant association between the parameters of the SF-36 and the clinical and radiological data. After performing several regression analyses it could be shown that the patient's mental health is a strong predictor of the postoperative vitality (r=0.803, p<0.01). However, none of the remaining parameters was able to predict the postoperative quality of life.

CONCLUSION

The patients in this study showed a reduced quality of life, independent of the method of surgical treatment. Although better radiological results could be seen for the combined procedure, regarding the postoperative quality of life no advantage could be proved compared with the dorsally stabilized patients. Furthermore, there was no relation between the radiological results and the quality of life parameters. Therefore, it can be assumed that the injury itself seems to be the main cause of the decreased quality of life after a burst fracture of the thoracolumbar transition.

摘要

引言

长期以来,后路固定一直是治疗胸腰椎爆裂骨折的标准术式,但在过去几年中,由于其更高的机械稳定性,前后路联合固定变得越来越重要。然而,目前尚无数据表明患者是否能从联合手术中受益于术后生活质量,以及与后路手术相比其优势何在。因此,在对胸腰段不稳定骨折患者进行配对分析的框架内对该问题进行了研究。

材料与方法

从1995年至2000年在我们诊所接受治疗的连续系列患者中,选择10例接受联合固定和10例接受单纯后路固定的患者纳入研究。用SF-36问卷回顾性总结他们的生活质量。分析X线片,计算Cobb角和矢状指数。仅纳入无合并症和神经功能缺损的胸腰段爆裂骨折患者。两个治疗组在性别、年龄和损伤的放射学模式方面进行了匹配。

结果

仅接受后路固定的患者在检查时矢状指数显示出明显的矫正丢失(术后为0.88±0.02,术后4年为0.77±0.03,p=0.01)。在接受联合治疗的患者组中,椎体矢状位轮廓方面没有统计学上相关的矫正丢失。与按年龄参考的正常人群相比,SF-36问卷显示两组的生活质量均有所下降,尤其是在身体健康参数方面。两组之间未观察到统计学上相关的差异。此外,SF-36的参数与临床和放射学数据之间没有统计学上相关的关联。进行多项回归分析后发现,患者的心理健康是术后活力的有力预测指标(r=0.803,p<0.01)。然而,其余参数均无法预测术后生活质量。

结论

本研究中的患者生活质量下降,与手术治疗方法无关。尽管联合手术在放射学上有更好的结果,但与后路固定的患者相比,在术后生活质量方面未证明有优势。此外,放射学结果与生活质量参数之间没有关系。因此,可以认为损伤本身似乎是胸腰段爆裂骨折后生活质量下降的主要原因。

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