Bossert Torsten, Battellini R, Kotowicz V, Falk V, Gummert J F, Mohr F W
Department of Cardiac Surgery, University of Leipzig, Heart Center, Germany.
J Card Surg. 2004 Jul-Aug;19(4):356-7. doi: 10.1111/j.0886-0440.2004.4095_11.x.
Syphilis can lead to saccular aneurysms of the thoracic aorta. Today syphilitic aortic aneurysms are rare. The average time from primary infections to the development of aortic aneurysms is 10 to 15 years. An 83-year-old man was admitted with a giant aneurysm of the descending thoracic aorta. The patient had first experienced subacute pain in the left hemithorax some weeks previously. Computer tomography scan detected an 11 x 11 cm aneurysm of the descending aorta. Serodiagnostic tests for syphilis were highly positive. Femoro-femoral bypass was initiated and a tube graft was interposed. The postoperative course was uneventful, the patient was discharged at the twentieth postoperative day. Histological examination of the aneurysmal wall showed typical syphilitic changes. Postoperatively, Penicillin G was given for 6 months. Three years later the patient remains asymptomatic. Although extremely rare today, tertiary syphilis should be considered in the differential diagnosis of thoracic aneurysms. In selected octogenarians replacement of the descending aorta is possible.
梅毒可导致胸主动脉囊状动脉瘤。如今,梅毒性主动脉瘤已较为罕见。从初次感染到主动脉瘤形成的平均时间为10至15年。一名83岁男性因降主动脉巨大动脉瘤入院。该患者数周前首次出现左半胸亚急性疼痛。计算机断层扫描检测到降主动脉有一个11×11厘米的动脉瘤。梅毒血清学诊断试验呈强阳性。开始进行股-股旁路手术并置入人工血管。术后过程顺利,患者于术后第20天出院。动脉瘤壁的组织学检查显示典型的梅毒病变。术后给予青霉素G治疗6个月。三年后患者仍无症状。尽管如今极为罕见,但在胸主动脉瘤的鉴别诊断中仍应考虑三期梅毒。对于特定的八旬老人,降主动脉置换是可行的。