Walsh Stephen R, Ferraro Mary Jane, Durand Marlene L
Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Diagn Microbiol Infect Dis. 2004 Jul;49(3):223-5. doi: 10.1016/j.diagmicrobio.2004.03.005.
A sentinel isolate of clindamycin-resistant Streptococcus pyogenes from a case of mixed aerobic-anaerobic necrotizing fasciitis prompted our clinical laboratory to change its protocol and subsequently perform routine susceptibility testing on all S. pyogenes isolated from blood and soft tissue specimens. Emerging clindamycin resistance may have serious implications in the treatment of severe S. pyogenes infections.
从一例需氧-厌氧混合性坏死性筋膜炎病例中分离出的一株对克林霉素耐药的化脓性链球菌警戒株,促使我们的临床实验室改变其方案,并随后对从血液和软组织标本中分离出的所有化脓性链球菌进行常规药敏试验。新出现的克林霉素耐药性可能对严重化脓性链球菌感染的治疗产生严重影响。