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通过投影算子进行的胎儿脑磁图重新分布

Fetal MEG redistribution by projection operators.

作者信息

Vrba Jiri, Robinson Stephen E, Mccubbin Jack, Lowery Curtis L, Eswaran Hari, Wilson James D, Murphy Pamela, Preissl Hubert

机构信息

VSM MedTech Ltd., Coquitlam, BC, Canada, V3K 7B2.

出版信息

IEEE Trans Biomed Eng. 2004 Jul;51(7):1207-18. doi: 10.1109/TBME.2004.827265.

Abstract

The fetal magnetoencephalogram (fMEG) is measured in the presence of large interference from the maternal and fetal magnetocardiograms. This interference can be efficiently attenuated by orthogonal projection of the corresponding spatial vectors. However, the projection operators redistribute the fMEG signal among sensors. Although redistribution can be readily accounted for in the forward solution, visual interpretation of the fMEG signal topography is made difficult. We have devised a general, model-independent method for correction of the redistribution effect that utilizes the assumption that we know in which channels the fMEG should be negligible (such channels are distant from the known fetal head position). In a simplified case where the fMEG can be explained by equivalent current dipoles, the correction can also be obtained from fitting the dipoles to the fMEG signal. The corrected fMEG signal topography then corresponds to the dipole forward solution, but without orthogonal projection. We illustrate the redistribution correction on an example of experimentally measured flash evoked fMEG.

摘要

胎儿脑磁图(fMEG)是在存在来自母体和胎儿心磁图的大量干扰的情况下进行测量的。这种干扰可以通过相应空间向量的正交投影得到有效衰减。然而,投影算子会在传感器之间重新分配fMEG信号。虽然在正向解中可以很容易地考虑到重新分配,但fMEG信号地形图的视觉解释变得困难。我们设计了一种通用的、与模型无关的方法来校正重新分配效应,该方法利用了我们知道哪些通道中的fMEG应该可以忽略不计的假设(这些通道远离已知的胎儿头部位置)。在一个简化的情况下,fMEG可以用等效电流偶极子来解释,校正也可以通过将偶极子拟合到fMEG信号来获得。校正后的fMEG信号地形图然后对应于偶极子正向解,但没有正交投影。我们以实验测量的闪光诱发fMEG为例说明了重新分配校正。

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