Bernier Roger, Midthun Karen
Centers for Disease Control and Prevention, 1600 Clifton Rd, Mailstop E-05, Atlanta, GA 30333.
Am J Public Health. 2004 Jun;94(6):914-7. doi: 10.2105/ajph.94.6.914.
Because of the potential for conflicts of interest, Salmon et al. propose in this issue the creation of an independent vaccine safety board to assume responsibility for assessing the safety of licensed vaccines.We believe that the current system at the Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) facilitates needed interactions between those involved in risk assessment and risk management, provides substantial safeguards against conflicts of interest, and results in sound decisions. The CDC, given its role in promoting immunization, may be perceived to have a greater potential conflict and plans to review its vaccine safety activities. Both agencies recognize the importance of transparency in considering vaccine safety and welcome the opportunity to work with the public and the medical community to improve the quality of scientific information and decisionmaking.
由于存在利益冲突的可能性，萨尔蒙等人在本期提议设立一个独立的疫苗安全委员会，负责评估已获许可疫苗的安全性。我们认为，美国食品药品监督管理局（FDA）和疾病控制与预防中心（CDC）的现行体系有助于参与风险评估和风险管理的各方进行必要的互动，提供了防范利益冲突的有力保障，并能做出合理决策。鉴于疾控中心在促进免疫接种方面的作用，可能会被认为存在更大的潜在冲突，因此该中心计划对其疫苗安全活动进行审查。这两个机构都认识到在考虑疫苗安全性时保持透明度的重要性，并欢迎有机会与公众和医学界合作，以提高科学信息和决策的质量。
