[一例华氏巨球蛋白血症中单克隆成分抗体特异性的评估]
[Evaluation of antibody specificity of the monoclonal component in a case of Waldenström's macroglobulinemia].
作者信息
Giovanna Zaninetta M, Moccia F, Paolo Mazzarello G, Mansuino P, Morra L
机构信息
Laboratorio di Analisi Chimico-Cliniche e Microbiologiche, Ospedale S. Martino, Genova.
出版信息
Ann Ital Med Int. 1992 Jan-Mar;7(1):42-5.
The antibody specificity of the monoclonal component was studied in a patient with Waldenström's macroglobulinemia who presented with high values of antistreptolysin O (ASO) titer and protein C which are clinical unlikely. Our methods demonstrated that two tests were falsely positive, inasmuch as the antibody activity of the monoclonal component was directed towards the albumin plus latex complex which theoretically is an inert immunological substrate.
在一名患有华氏巨球蛋白血症的患者中研究了单克隆成分的抗体特异性，该患者抗链球菌溶血素O（ASO）滴度和蛋白C值很高，这在临床上不太可能出现。我们的方法表明两项检测结果呈假阳性，因为单克隆成分的抗体活性针对白蛋白加乳胶复合物，理论上这是一种惰性免疫底物。
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