Altundag K, Yalcin S, Ozkaya O, Guler N
Institute of Oncology, Department of Pathology, Hacettepe School of Medicine, Ankara, Turkey.
Onkologie. 2004 Jun;27(3):291-3. doi: 10.1159/000077981.
The incidence of multiple primary cancers is reported to be 0.3-4.3%.
A 70-year-old man was admitted to the hospital because of fatigue, weight loss, epigastric pain with melena. A biopsy taken from a tumoral lesion in the gastric corpus revealed squamous cell carcinoma. A nodular lesion was also detected on the nasal columella and biopsy from this lesion also showed squamous cell carcinoma. Computed tomography performed as a part of metastatic work-up revealed a lesion in the left pulmonary lower lobe. Bronchoscopic biopsy from this lesion also demonstrated squamous cell carcinoma.
We report a case with synchronous squamous cell carcinoma of the lung, skin and stomach and discuss the multiple synchronous occurrence of carcinoma with the same histopathology in different sites with a review of the literature.
据报道，多原发性癌的发病率为0.3%-4.3%。
一名70岁男性因疲劳、体重减轻、上腹部疼痛伴黑便入院。取自胃体部肿瘤性病变的活检显示为鳞状细胞癌。鼻小柱上也检测到一个结节性病变，该病变的活检也显示为鳞状细胞癌。作为转移灶检查一部分进行的计算机断层扫描显示左肺下叶有一个病变。该病变的支气管镜活检也证实为鳞状细胞癌。
我们报告了一例同时发生肺、皮肤和胃鳞状细胞癌的病例，并结合文献复习讨论了同一组织病理学类型的癌在不同部位的多灶同时发生情况。
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