Sex differences in body fat distribution and carotid intima media thickness: cross sectional survey using data from the British regional heart study.
作者信息
Lawlor Debbie A, Ebrahim Shah, Whincup Peter, Sterne Jonathan, Papacosta Olia, Wannamethee Goya, Dhanjil Surinder, Griffin Maura, Nicolaides Andrew N, Davey Smith George
机构信息
Department of Social Medicine, University of Bristol, UK.
出版信息
J Epidemiol Community Health. 2004 Aug;58(8):700-4. doi: 10.1136/jech.2003.014001.
Abstract
OBJECTIVE
To determine the role of central adiposity in explaining sex differences in carotid intima media thickness (IMT).
DESIGN
Cross sectional survey.
SETTING
Two British towns.
PARTICIPANTS
800 men and women aged 56-75 years.
MAIN OUTCOME MEASURES
Carotid IMT.
RESULTS
There was a continuous linear association between waist-hip ratio and IMT in both men and women. The magnitude of the association between waist to hip ratio and IMT was identical in both sexes. In age adjusted analyses IMT was 14% greater in men compared with women (age adjusted male to female ratio of geometric means 1.14; 95% confidence interval 1.07 to 1.21) with adjustment for waist to hip ratio this attenuated to no difference (1.00; 0.92 to 1.09). Adjustment for body mass index and for lifestyle risk factors had very little effect on the sex difference in mean intima media thickness.
CONCLUSIONS
Sex differences in body fat distribution may explain sex differences in arterial atherosclerosis.
摘要
相似文献
1
Sex differences in body fat distribution and carotid intima media thickness: cross sectional survey using data from the British regional heart study.
J Epidemiol Community Health. 2004 Aug;58(8):700-4. doi: 10.1136/jech.2003.014001.
2
Association of waist and hip circumference with 12-year progression of carotid intima-media thickness in elderly women.
Int J Obes (Lond). 2007 Sep;31(9):1406-11. doi: 10.1038/sj.ijo.0803613. Epub 2007 Mar 20.
3
Risk of cardiovascular disease in a cohort of HIV-infected adults: a study using carotid intima-media thickness and coronary artery calcium score.
Clin Infect Dis. 2006 Dec 1;43(11):1482-9. doi: 10.1086/509575. Epub 2006 Oct 31.
4
Effect of age and sex on carotid intima-media thickness, elasticity and brachial endothelial function in healthy adults: the cardiovascular risk in Young Finns Study.
Eur Heart J. 2008 May;29(9):1198-206. doi: 10.1093/eurheartj/ehm556. Epub 2007 Dec 12.
5
[C-reactive protein and carotid intima-media thickness in a population of middle-aged Koreans].
J Prev Med Public Health. 2009 Jan;42(1):29-34. doi: 10.3961/jpmph.2009.42.1.29.
6
Sex-dependent variables in the modulation of postalimentary lipemia.
Nutrition. 2006 Jan;22(1):9-15. doi: 10.1016/j.nut.2005.05.004. Epub 2005 Oct 12.
7
Lifecourse socioeconomic position, C-reactive protein, and carotid intima-media thickness in young adults: the cardiovascular risk in Young Finns Study.
Arterioscler Thromb Vasc Biol. 2005 Oct;25(10):2197-202. doi: 10.1161/01.ATV.0000183729.91449.6e. Epub 2005 Aug 25.
8
Association of carotid intima-medial thickness and indices of arterial stiffness with cardiovascular disease outcomes in CKD.
Am J Kidney Dis. 2007 Oct;50(4):622-30. doi: 10.1053/j.ajkd.2007.07.012.
9
Influence of HDL cholesterol on preclinical carotid atherosclerosis in familial hypercholesterolemia.
Arterioscler Thromb Vasc Biol. 2006 May;26(5):1107-13. doi: 10.1161/01.ATV.0000218507.95149.42. Epub 2006 Mar 23.
10
The intake of flavonoids and carotid atherosclerosis: the Kuopio Ischaemic Heart Disease Risk Factor Study.
Br J Nutr. 2007 Oct;98(4):814-8. doi: 10.1017/S0007114507744410. Epub 2007 Apr 30.
引用本文的文献
1
Association Between Risk Factors in Childhood and Sex Differences in Prevalence of Carotid Artery Plaques and Intima-Media Thickness in Mid-Adulthood in the Childhood Determinants of Adult Health Study.
J Am Heart Assoc. 2023 Mar 21;12(6):e027206. doi: 10.1161/JAHA.122.027206. Epub 2023 Mar 9.
2
Sex Differences in Cardiac Troponin I and T and the Prediction of Cardiovascular Events in the General Population.
Clin Chem. 2021 Oct 1;67(10):1351-1360. doi: 10.1093/clinchem/hvab109.
3
Association between Sports Participation in Early Life and Arterial Intima-Media Thickness among Adults.
Medicina (Kaunas). 2018 Nov 13;54(5):85. doi: 10.3390/medicina54050085.
4
Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies-Statement From ATVB Council.
Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):292-303. doi: 10.1161/ATVBAHA.117.309524. Epub 2018 Jan 4.
5
Gender-based differences in the relationship between fatty liver disease and atherosclerosis.
Cardiovasc J Afr. 2016;27(5):281-286. doi: 10.5830/CVJA-2016-014. Epub 2016 Mar 14.
6
Cognitive Avoidant Coping Is Associated with Higher Carotid Intima Media Thickness Among Middle-Aged Adults.
Int J Behav Med. 2015 Oct;22(5):597-604. doi: 10.1007/s12529-014-9457-8.
7
Advanced practice nurses facilitating clinical translational research.
Clin Med Res. 2010 Dec;8(3-4):131-4. doi: 10.3121/cmr.2010.911. Epub 2010 Aug 3.
8
Differences in atherosclerosis according to area level socioeconomic deprivation: cross sectional, population based study.
BMJ. 2009 Oct 27;339:b4170. doi: 10.1136/bmj.b4170.
9
Psychological, social and biological determinants of ill health (pSoBid): study protocol of a population-based study.
BMC Public Health. 2008 Apr 21;8:126. doi: 10.1186/1471-2458-8-126.
10
Adiponectin and the cardiovascular system: from risk to disease.
Intern Emerg Med. 2007 Oct;2(3):165-76. doi: 10.1007/s11739-007-0027-9. Epub 2007 Oct 1.
本文引用的文献
1
Central overweight and obesity in British youth aged 11-16 years: cross sectional surveys of waist circumference.
BMJ. 2003 Mar 22;326(7390):624. doi: 10.1136/bmj.326.7390.624.
2
Role of endogenous oestrogen in aetiology of coronary heart disease: analysis of age related trends in coronary heart disease and breast cancer in England and Wales and Japan.
BMJ. 2002 Aug 10;325(7359):311-2. doi: 10.1136/bmj.325.7359.311.
3
Sex matters: secular and geographical trends in sex differences in coronary heart disease mortality.
BMJ. 2001 Sep 8;323(7312):541-5. doi: 10.1136/bmj.323.7312.541.
4
Age and sex differences in the relationship between inherited and lifestyle risk factors and subclinical carotid atherosclerosis: the Tromsø study.
Atherosclerosis. 2001 Feb 1;154(2):437-48. doi: 10.1016/s0021-9150(00)00486-x.
5
Impact of diabetes on coronary artery disease in women and men: a meta-analysis of prospective studies.
Diabetes Care. 2000 Jul;23(7):962-8. doi: 10.2337/diacare.23.7.962.
6
Sex differences in the relationship of risk factors to subclinical carotid atherosclerosis measured 15 years later : the Tromsø study.
Stroke. 2000 Mar;31(3):574-81. doi: 10.1161/01.str.31.3.574.
7
Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women: the British Regional Heart Study.
Stroke. 1999 Apr;30(4):841-50. doi: 10.1161/01.str.30.4.841.
8
Abdominal adiposity and coronary heart disease in women.
JAMA. 1998 Dec 2;280(21):1843-8. doi: 10.1001/jama.280.21.1843.
9
Myth and paradox of coronary risk and the menopause.
Lancet. 1998 May 9;351(9113):1425-7. doi: 10.1016/S0140-6736(97)11321-6.
10
Increased common carotid intima-media thickness. Adaptive response or a reflection of atherosclerosis? Findings from the Rotterdam Study.
Stroke. 1997 Dec;28(12):2442-7. doi: 10.1161/01.str.28.12.2442.
Zotero 插件