人类淋巴母细胞系中的核糖体顺反子活性是否增加？
Is ribosomal cistron activity increased in human lymphoblastoid cell lines?
作者信息
Gupta N J, Hopwood V L, Pathak S
机构信息
Department of Cell Biology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
出版信息
In Vivo. 1992 Mar-Apr;6(2):125-8.
The genomic activity of nucleolar organizer regions (NORs) in eight human B-cell lymphoblastoid cell lines was studied following the routinely used Ag-NOR technique. The results demonstrate that (a) Ag-NORs are located in the short arms of D- and G-group chromosomes, (b) two out of eight cell lines have 66.7% and 49.0% of metaphases, respectively, with 9 to 10 active Ag-NORs, and (c) as a whole, Ag-NOR activity is much higher in B-cell lines as compared with conventional 72-hr peripheral blood lymphocyte (T-cell) harvests.
采用常规的银染核仁组织区（Ag-NOR）技术，对8个人类B淋巴细胞系中的核仁组织区（NORs）的基因组活性进行了研究。结果表明：（a）Ag-NORs位于D组和G组染色体的短臂上；（b）8个细胞系中有2个分别有66.7%和49.0%的中期细胞具有9到10个活性Ag-NORs；（c）总体而言，与传统的72小时外周血淋巴细胞（T细胞）收获物相比，B细胞系中的Ag-NOR活性要高得多。
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