Van der Donck I, Mulliez E, Blanckaert J
Department of Ophthalmology, University Hospitals K.U. Leuven, Leuven, Belgium.
Bull Soc Belge Ophtalmol. 2004(292):53-6.
We report a case of anisocoria in a 6-year old child who felt out of an inflatable swimming pool in the garden. After instillation of pilocarpine 1% the dilated pupil constricted, which is an important clinical sign associated with intracranial trauma. There was evidence of exposure to angel's trumpet (Brugmansia arborea), a plant known to contain anticholinergic substances. As the results of further neurological examination turned out to be normal, we believe the mydriasis was due to an accidental exposure to angel's trumpet. The time lag between exposure and presentation at the emergency room, the probably low volume of the plant extract in the eye and the unpredictable concentration of alkaloids in the plant, can influence and question the reliability of the pilocarpine test in this case.
我们报告一例6岁儿童的瞳孔不等大病例,该儿童从花园里的充气游泳池中摔出。滴入1%毛果芸香碱后,扩大的瞳孔收缩,这是与颅内创伤相关的重要临床体征。有证据表明该儿童接触过天使的号角(黄花曼陀罗),这是一种已知含有抗胆碱能物质的植物。由于进一步的神经学检查结果正常,我们认为瞳孔散大是由于意外接触天使的号角所致。接触植物与在急诊室就诊之间的时间间隔、眼中可能少量的植物提取物以及植物中生物碱浓度的不可预测性,可能会影响并质疑该病例中毛果芸香碱试验的可靠性。