Merlini G
Neth J Med. 2004 Apr;62(4):104-5.
Systemic amyloidoses are a wide group of diseases with different courses, treatments and prognoses. Unequivocal typing of amyloid deposits is important for correct diagnosis and appropriate treatment. At present, the most effective therapeutic approach is based on eliminating the supply of amyloidogenic precursor. New effective therapies will stem from our improved knowledge of the molecular mechanisms of amyloidosis.
全身性淀粉样变性是一大类病程、治疗方法和预后各异的疾病。明确淀粉样沉积物的分型对于正确诊断和恰当治疗至关重要。目前,最有效的治疗方法是基于消除淀粉样蛋白生成前体的供应。新的有效疗法将源于我们对淀粉样变性分子机制的深入了解。