Cornu Olivier, Manil Olivier, Godts Bernard, Naets Bénédicte, Van Tomme John, Delloye Christian, Banse Xavier
Orthopaedic Research Laboratory, Université Catholique de Louvain, Brussels, Belgium.
Acta Orthop Scand. 2004 Jun;75(3):303-8. doi: 10.1080/00016470410001231.
The need for safe bone allografts is increasing and preservation of femoral heads from patients being operated on with hip arthroplasty should be encouraged. However, should we preserve femoral heads from patients operated on for neck fracture as tissue mechanical quality may not be satisfactory?
We compared the evolution of stiffness and compactness of fresh-frozen morselized bone obtained from osteoarthrotic femoral heads and those from neck fractures. Both materials were also compared after freeze-drying and irradiation. We used 6 osteoarthrotic and 6 neck-fracture femoral heads to prepare 4 batches of morselized bone. 18 samples from each batch were impacted in a contained cylinder. Frozen bone grafts were tested after thawing at room temperature for 2 hours and freeze-dried grafts were tested after 30 minutes of rehydration.
The stiffness of fresh-frozen neck fracture bone was lower than that of fresh-frozen osteoarthrotic bone at 150 impactions. The stiffness of freeze-dried irradiated bone was higher than that of the fresh-frozen bone and did not differ between osteoarthrotic and neck-fracture bone.
Solvent-treated freeze-dried bone from femoral heads procured during arthroplasty for sub-capital hip fractures represents a valuable source of material for allografts, addressing concerns regarding serological testing, medical history and bone quality.
对安全骨移植的需求日益增加，应鼓励保存接受髋关节置换手术患者的股骨头。然而，对于因颈部骨折而接受手术的患者，其股骨头是否值得保存，因为其组织力学质量可能并不理想？
我们比较了从骨关节炎性股骨头和颈部骨折患者获取的新鲜冷冻碎骨的硬度和密实度的变化情况。对这两种材料在冻干和辐照后也进行了比较。我们使用6个骨关节炎性股骨头和6个颈部骨折股骨头制备了4批碎骨。每批取18个样本在一个密闭圆柱体中进行冲击试验。冷冻骨移植材料在室温下解冻2小时后进行测试，冻干骨移植材料在复水30分钟后进行测试。
在150次冲击时，新鲜冷冻的颈部骨折骨的硬度低于新鲜冷冻的骨关节炎性骨。冻干辐照骨的硬度高于新鲜冷冻骨，且在骨关节炎性骨和颈部骨折骨之间无差异。
在髋关节置换术中获取的、用于治疗股骨头下型髋部骨折的经溶剂处理的冻干骨，是一种有价值的骨移植材料来源，解决了血清学检测、病史及骨质量方面的问题。
