Callaway Edward M
Systems Neurobiology Laboratories, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
Neuron. 2004 Jul 22;43(2):156-8. doi: 10.1016/j.neuron.2004.07.006.
In this issue of Neuron, Stepanyants et al. embark on quantitative analyses of the axonal and dendritic arbors of cortical neurons. They test whether the paths taken by axons actually bring them closer to their true synaptic partners than they would have gotten by chance encounters based on the same axon trajectories. The results depend on the type of presynaptic neuron. Inhibitory cells take paths that explicitly link them to their actual partners while excitatory axons are as likely to have close encounters with actual partners as with other neurons. These results suggest that the mechanisms for selectivity depend on the type of presynaptic neuron.
在本期《神经元》杂志中，斯捷潘扬茨等人对皮层神经元的轴突和树突分支进行了定量分析。他们测试了轴突所走的路径是否真的能让它们比基于相同轴突轨迹的随机相遇更接近其真正的突触伙伴。结果取决于突触前神经元的类型。抑制性细胞所走的路径将它们明确地与其实际伙伴相连，而兴奋性轴突与实际伙伴近距离接触的可能性与和其他神经元接触的可能性相同。这些结果表明，选择性机制取决于突触前神经元的类型。
