Inoue Takashi, Ogasawara Kuniaki, Beppu Takaaki, Ogawa Akira
Department of Neurosurgery, Iwate Medical University School of Medicine, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan.
Surg Neurol. 2004 Aug;62(2):151-4; discussion 154-5. doi: 10.1016/j.surneu.2003.08.031.
Magnetic resonance imaging (MRI) can provide a preoperative diagnosis of gliomatosis cerebri, but the findings sometimes do not correspond with the clinical symptoms or histologic findings.
Three-dimensional anisotropy contrast (3DAC) imaging was used to assess damage to the neuronal fibers in two patients with gliomatosis cerebri who presented with only mental deterioration. Conventional MRI depicted markedly abnormal findings consisting of widespread areas of abnormally high signal intensity in the corpus callosum and in the bilateral white matter in both cases. In contrast, 3-D AC imaging showed no abnormality except for small dark areas in the corpus callosum or white matter.
3-D AC imaging provides more accurate information about damage to the neuronal fibers in cases of gliomatosis cerebri than other MRI techniques.
磁共振成像（MRI）能够对大脑胶质瘤病进行术前诊断，但有时其结果与临床症状或组织学发现并不相符。
采用三维各向异性对比（3DAC）成像评估了两名仅表现为精神衰退的大脑胶质瘤病患者的神经纤维损伤情况。两名患者的常规MRI均显示明显异常结果，胼胝体和双侧白质广泛区域存在异常高信号强度。相比之下，3-D AC成像显示除胼胝体或白质中有小的暗区外无异常。
与其他MRI技术相比，3-D AC成像能提供关于大脑胶质瘤病病例中神经纤维损伤的更准确信息。
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