• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Assessing the function of genetic variants in candidate gene association studies.

作者信息

Rebbeck Timothy R, Spitz Margaret, Wu Xifeng

机构信息

Department of Biostatistics and Epidemiology, and Abramson Cancer Center, University of Pennsylvania School of Medicine, 904 Blockley Hall, 423 Guardian Drive, Philadelphia, Pennsylvania 19104, USA.

出版信息

Nat Rev Genet. 2004 Aug;5(8):589-97. doi: 10.1038/nrg1403.

DOI:10.1038/nrg1403
PMID:15266341
Abstract
摘要

相似文献

1
Assessing the function of genetic variants in candidate gene association studies.评估候选基因关联研究中基因变异的功能。
Nat Rev Genet. 2004 Aug;5(8):589-97. doi: 10.1038/nrg1403.
2
Use of classification trees for association studies.分类树在关联研究中的应用。
Genet Epidemiol. 2000 Dec;19(4):323-32. doi: 10.1002/1098-2272(200012)19:4<323::AID-GEPI4>3.0.CO;2-5.
3
Selection of candidate genes for population studies.
IARC Sci Publ. 1999(148):23-36.
4
A CXCL2 tandem repeat promoter polymorphism is associated with susceptibility to severe sepsis in the Spanish population.CXCL2串联重复启动子多态性与西班牙人群严重脓毒症易感性相关。
Genes Immun. 2006 Mar;7(2):141-9. doi: 10.1038/sj.gene.6364280.
5
Large-scale evaluation of genetic variants in candidate genes for colorectal cancer risk in the Nurses' Health Study and the Health Professionals' Follow-up Study.护士健康研究和卫生专业人员随访研究中对结直肠癌风险候选基因的遗传变异进行大规模评估。
Cancer Epidemiol Biomarkers Prev. 2008 Feb;17(2):311-9. doi: 10.1158/1055-9965.EPI-07-0195.
6
Genetic diversity and genetic burden in humans.
Infect Genet Evol. 2006 Mar;6(2):154-62. doi: 10.1016/j.meegid.2005.04.002. Epub 2005 Oct 24.
7
Psychiatric genetics--the new era: genetic research and some clinical implications.
Br Med Bull. 2005 Dec 19;73-74:107-22. doi: 10.1093/bmb/ldh055. Print 2005.
8
Current computational methods for prioritizing candidate regulatory polymorphisms.用于对候选调控多态性进行优先级排序的当前计算方法。
Methods Mol Biol. 2009;569:89-114. doi: 10.1007/978-1-59745-524-4_5.
9
A bioinformatics approach for the phenotype prediction of nonsynonymous single nucleotide polymorphisms in human cytochromes P450.一种用于预测人类细胞色素P450中非同义单核苷酸多态性表型的生物信息学方法。
Drug Metab Dispos. 2009 May;37(5):977-91. doi: 10.1124/dmd.108.026047. Epub 2009 Feb 9.
10
CYP3A5 gene polymorphism and risk of prostate cancer in a Japanese population.
Cancer Lett. 2005 Jul 28;225(2):237-43. doi: 10.1016/j.canlet.2005.03.009.

引用本文的文献

1
Evolutionary analyses reveal immune cell receptor GPR84 as a conserved receptor for bacteria-derived molecules.进化分析表明,免疫细胞受体GPR84是一种针对细菌衍生分子的保守受体。
iScience. 2022 Sep 6;25(10):105087. doi: 10.1016/j.isci.2022.105087. eCollection 2022 Oct 21.
2
Single-Nucleotide Polymorphisms (SNP) Mining and Their Effect on the Tridimensional Protein Structure Prediction in a Set of Immunity-Related Expressed Sequence Tags (EST) in Atlantic Salmon ().大西洋鲑鱼一组免疫相关表达序列标签(EST)中的单核苷酸多态性(SNP)挖掘及其对三维蛋白质结构预测的影响。
Front Genet. 2020 Feb 27;10:1406. doi: 10.3389/fgene.2019.01406. eCollection 2019.
3
Genetic Variation and Response to Neurocritical Illness: a Powerful Approach to Identify Novel Pathophysiological Mechanisms and Therapeutic Targets.
遗传变异与神经危重症反应:一种识别新的病理生理机制和治疗靶点的强大方法。
Neurotherapeutics. 2020 Apr;17(2):581-592. doi: 10.1007/s13311-020-00837-2.
4
Single Nucleotide Polymorphism Genotyping in Single-Molecule Electronic Circuits.单分子电子电路中的单核苷酸多态性基因分型
Adv Sci (Weinh). 2017 Jul 26;4(11):1700158. doi: 10.1002/advs.201700158. eCollection 2017 Nov.
5
A new panel of SNPs to assess thyroid carcinoma risk: a pilot study in a Brazilian admixture population.一组用于评估甲状腺癌风险的新型单核苷酸多态性:巴西混合人群中的一项试点研究。
BMC Med Genet. 2017 Nov 25;18(1):140. doi: 10.1186/s12881-017-0502-8.
6
The genetic epidemiology of substance use disorder: A review.物质使用障碍的遗传流行病学:综述。
Drug Alcohol Depend. 2017 Nov 1;180:241-259. doi: 10.1016/j.drugalcdep.2017.06.040. Epub 2017 Aug 1.
7
SNP variants associated with non-Hodgkin lymphoma (NHL) correlate with human leukocyte antigen (HLA) class II expression.与非霍奇金淋巴瘤(NHL)相关的单核苷酸多态性(SNP)变体与人类白细胞抗原(HLA)Ⅱ类表达相关。
Sci Rep. 2017 Jan 31;7:41400. doi: 10.1038/srep41400.
8
Evaluation of DNA variants associated with androgenetic alopecia and their potential to predict male pattern baldness.与雄激素性脱发相关的DNA变异评估及其预测男性型秃发的潜力。
PLoS One. 2015 May 22;10(5):e0127852. doi: 10.1371/journal.pone.0127852. eCollection 2015.
9
RACK1 is a candidate gene associated with the prognosis of patients with early stage non-small cell lung cancer.RACK1是与早期非小细胞肺癌患者预后相关的候选基因。
Oncotarget. 2015 Feb 28;6(6):4451-66. doi: 10.18632/oncotarget.2865.
10
DFLAT: functional annotation for human development.DFLAT:人类发育的功能注释。
BMC Bioinformatics. 2014 Feb 7;15:45. doi: 10.1186/1471-2105-15-45.