Liu You-ning
Department of Respiratory Disease, Chinese PLA General Hospital, Beijing 100853, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004 Jun;26(3):219-20.
Diffuse panbronchiolitis is a new respiratory tract disease and was initially found in Japan. Strong association between race-dependent antigens and diffuse panbronchiolitis suggests a genetic predisposition to the disease. 14-member ring and 15-member ring macrolides have been proved to have significant therapeutical effect on diffuse panbronchiolitis. The discovery of diffuse panbronchiolitis and the advent of macrolide therapy for this disease suggests that clinicians should pay more attention to racial difference of some diseases and never overlook any accidental phenomenon in clinical practice.
弥漫性泛细支气管炎是一种新发现的呼吸道疾病,最初在日本被发现。种族依赖性抗原与弥漫性泛细支气管炎之间的强关联表明该疾病存在遗传易感性。已证实14元环和15元环大环内酯类药物对弥漫性泛细支气管炎有显著治疗效果。弥漫性泛细支气管炎的发现以及针对该疾病的大环内酯类药物治疗的出现表明,临床医生应更加关注某些疾病的种族差异,在临床实践中绝不能忽视任何偶然现象。