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3.0T 磁共振成像在肌肉骨骼系统中的应用:弛豫时间与图像对比

Musculoskeletal MRI at 3.0 T: relaxation times and image contrast.

作者信息

Gold Garry E, Han Eric, Stainsby Jeff, Wright Graham, Brittain Jean, Beaulieu Christopher

机构信息

Department of Radiology, Stanford University, 300 Pasteur Dr., Grant Bldg. S0-68B, Stanford, CA 94305-5105, USA.

出版信息

AJR Am J Roentgenol. 2004 Aug;183(2):343-51. doi: 10.2214/ajr.183.2.1830343.

Abstract

OBJECTIVE

The purpose of our study was to measure relaxation times in musculoskeletal tissues at 1.5 and 3.0 T to optimize musculoskeletal MRI methods at 3.0 T.

MATERIALS AND METHODS

In the knees of five healthy volunteers, we measured the T1 and T2 relaxation times of cartilage, synovial fluid, muscle, marrow, and fat at 1.5 and 3.0 T. The T1 relaxation times were measured using a spiral Look-Locker sequence with eight samples along the T1 recovery curve. The T2 relaxation times were measured using a spiral T2 preparation sequence with six echoes. Accuracy and repeatability of the T1 and T2 measurement sequences were verified in phantoms.

RESULTS

T1 relaxation times in cartilage, muscle, synovial fluid, marrow, and subcutaneous fat at 3.0 T were consistently higher than those measured at 1.5 T. Measured T2 relaxation times were reduced at 3.0 T compared with 1.5 T. Relaxation time measurements in vivo were verified using calculated and measured signal-to-noise results. Relaxation times were used to develop a high-resolution protocol for T2-weighted imaging of the knee at 3.0 T.

CONCLUSION

MRI at 3.0 T can improve resolution and speed in musculoskeletal imaging; however, interactions between field strength and relaxation times need to be considered for optimal image contrast and signal-to-noise ratio. Scanning can be performed in shorter times at 3.0 T using single-average acquisitions. Efficient higher-resolution imaging at 3.0 T can be done by increasing the TR to account for increased T1 relaxation times and acquiring thinner slices than at 1.5 T.

摘要

目的

我们研究的目的是测量肌肉骨骼组织在1.5 T和3.0 T时的弛豫时间,以优化3.0 T时的肌肉骨骼磁共振成像(MRI)方法。

材料与方法

在五名健康志愿者的膝关节中,我们测量了软骨、滑液、肌肉、骨髓和脂肪在1.5 T和3.0 T时的T1和T2弛豫时间。T1弛豫时间采用螺旋Look-Locker序列测量,沿T1恢复曲线有八个样本。T2弛豫时间采用具有六个回波的螺旋T2准备序列测量。T1和T2测量序列的准确性和可重复性在体模中得到验证。

结果

3.0 T时软骨、肌肉、滑液、骨髓和皮下脂肪的T1弛豫时间始终高于1.5 T时测量的值。与1.5 T相比,3.0 T时测量的T2弛豫时间缩短。体内弛豫时间测量通过计算和测量的信噪比结果得到验证。弛豫时间用于制定3.0 T时膝关节T2加权成像的高分辨率方案。

结论

3.0 T的MRI可提高肌肉骨骼成像的分辨率和速度;然而,为获得最佳图像对比度和信噪比,需要考虑场强与弛豫时间之间的相互作用。使用单次平均采集,在3.0 T时可以在更短的时间内进行扫描。通过增加TR以适应增加的T1弛豫时间并采集比1.5 T更薄的切片,可以在3.0 T时实现高效的高分辨率成像。

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