弱光牛角瓜对正常及四氧嘧啶诱导的糖尿病大鼠的影响。
Effect of Caralluma attenuata in normal and alloxan induced diabetic rats.
作者信息
Jayakar B, Rajkapoor B, Suresh B
机构信息
Department of Pharmaceutical Chemistry, Vinayaka Mission's College of Pharmacy, Yercaud Road, Salem - 636 008, Tamil Nadu, India.
出版信息
J Herb Pharmacother. 2004;4(1):35-40.
The hypoglycemic effect of aqueous and alcoholic extracts of whole plant Caralluma attenuata was investigated in both normal and alloxan induced diabetic rats. The blood glucose levels were measured at 0, 1, 2 and 3 h after the treatment. The aqueous and alcoholic extracts of C. attenuata (100 mg/kg) reduced the blood glucose level of normal rat from 84.5 +/- 2.0 to 68.5 +/- 2.8 mg/dl and 82.6 +/- 1.8 to 67.4 +/- 2.8 mg/dl, respectively, 3h after oral administration (P < 0.001). Blood glucose levels in alloxan induced diabetic rats were also significantly lowered from 316 +/- 3.32 to 162 +/- 2.76 and 324 +/- 4.10 to 150 +/- 3.94 mg/dl, respectively, 3 h after oral administration (P < 0.001).
在正常大鼠和四氧嘧啶诱导的糖尿病大鼠中，研究了全株纤细肉珊瑚水提取物和醇提取物的降血糖作用。在治疗后0、1、2和3小时测量血糖水平。纤细肉珊瑚水提取物和醇提取物（100mg/kg）在口服给药3小时后，分别将正常大鼠的血糖水平从84.5±2.0降至68.5±2.8mg/dl，以及从82.6±1.8降至67.4±2.8mg/dl（P<0.001）。四氧嘧啶诱导的糖尿病大鼠在口服给药3小时后，血糖水平也分别显著从316±3.32降至162±2.76，以及从324±4.10降至150±3.94mg/dl（P<0.001）。
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