Hodzic Jasmin, Golka Klaus, Schulze Harald
Department of Urology, Ruprecht-Karls University, Heidelberg, Germany.
Med Sci Monit. 2004 Aug;10(8):CS46-8. Epub 2004 Jul 23.
Testicular tumors in general can be classified as seminoma, embryonal carcinoma, teratocarcinoma, choriocarcinoma, and mixed tumors. Nevertheless, other histological types may also be observed. In rare cases, primary or secondary neuroendocrine tumors derived from chromaffine cells can be observed in the testicle.
A 51-year-old patient was hospitalized on account of a two-month-old painless tumescence of the right testicle. Radical orchiectomy revealed a solid, inhomogeneous intratesticular tumor 3 cm in diameter. Pathohistological findings and immunohistochemical staining with different neuroendocrine markers revealed a testicular carcinoid classified as pT1. The excretion of 5-hydroxyindole-acetic acid (5-HIAA) was within the normal range. No further carcinoid tumor site was found.
In case of a testicular carcinoid, exclusion of a primary carcinoid tumor site in other organs is mandatory.
睾丸肿瘤一般可分为精原细胞瘤、胚胎癌、畸胎癌、绒毛膜癌和混合性肿瘤。然而,也可能观察到其他组织学类型。在罕见情况下,可在睾丸中观察到源自嗜铬细胞的原发性或继发性神经内分泌肿瘤。
一名51岁患者因右侧睾丸无痛性肿大两个月入院。根治性睾丸切除术显示一个直径3厘米的实性、不均匀的睾丸内肿瘤。病理组织学检查结果以及用不同神经内分泌标志物进行的免疫组化染色显示为pT1期睾丸类癌。5-羟色胺酸(5-HIAA)排泄在正常范围内。未发现其他类癌肿瘤部位。
对于睾丸类癌,必须排除其他器官的原发性类癌肿瘤部位。