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[肝脏发育异常性囊肿:我们的经验]

[Dysplastic cysts of the liver: our experience].

作者信息

Nardello O, Muggianu M, Cabras V, Farina G P, Cagetti M

机构信息

Clinica Chirurgica, Istituto di Chirurgia, Università degli Studi di Cagliari, Cagliari, Italy.

出版信息

Minerva Chir. 2004 Aug;59(4):351-62.

Abstract

AIM

Systematic surveys with advanced non-invasive imaging techniques have revealed that hepatic cysts are quite common in the general population. Therefore, we retrospectively examined our case series and compared it with the literature.

METHODS

Between January 1990 and December 2000, 228 patients with non-parasitic liver cysts were referred to the outpatients section of the Department of Surgery of the University of Cagliari and 23 were submitted to treatment: 14 patients (60.8%) for solitary cyst and 9 (39.2%) for multiple simple cysts of the liver. One patient (4.5%) had right upper quadrant pain. Eleven (47.8%) patients were asymptomatic: 7 (63.7%) required treatment for other pathologies, 3 (27.3%) for a progressive enlargement of the cyst and 1 (9%) for a suspected hydatid disease. Mean diameter of the treated cysts measured by preoperative CT or US was 8.8 cm (range 7-14). Percutaneous aspiration-injection reaspiration (PAIR) was performed in 5 patients (21.7%), US-guided in 2 cases (40%) and CT-guided in 3 (60%). Twenty patients (86.9%) underwent cysts unroofing, 18 (78.2%) with open surgical fenestration and the latest 2 cases with a laparoscopic approach. Two patients had PAIR as second treatment for recurrence: CT-guided in one and US-guided in the other case.

RESULTS

Four (25%) out of 16 patients treated exclusively for cystic liver disease, had fever in 3 cases and nausea and vomiting in 1 case; 8 patients (50%) had an intraperitoneal drainage for a mean of 6-7 days (range 4-11) and of 116 cc of serum-hematic liquid.

CONCLUSIONS

In our opinion the choice of an adequate treatment must be based on an accurate evaluation of the clinical aspects of the patients and on the characteristics of cystic lesions such as number, size and location. These data let us to choose a surgical treatment rather than a strict US follow-up and to get the best outcome in terms of absence of recurrence, and less biological and economic costs.

摘要

目的

采用先进的非侵入性成像技术进行的系统调查显示,肝囊肿在普通人群中相当常见。因此,我们回顾性研究了我们的病例系列,并与文献进行了比较。

方法

1990年1月至2000年12月期间,228例非寄生虫性肝囊肿患者被转诊至卡利亚里大学外科门诊,其中23例接受了治疗:14例(60.8%)为孤立性囊肿,9例(39.2%)为多发性单纯性肝囊肿。1例患者(4.5%)有右上腹疼痛。11例(47.8%)患者无症状:7例(63.7%)因其他疾病需要治疗,3例(27.3%)因囊肿逐渐增大需要治疗,1例(9%)因疑似包虫病需要治疗。术前CT或超声测量的治疗囊肿平均直径为8.8厘米(范围7-14厘米)。5例患者(21.7%)接受了经皮穿刺抽吸-注射-再抽吸(PAIR)治疗,2例(40%)在超声引导下进行,3例(60%)在CT引导下进行。20例患者(86.9%)接受了囊肿开窗术,18例(78.2%)采用开放手术开窗,最近2例采用腹腔镜手术。2例患者因复发接受PAIR作为二次治疗:1例在CT引导下,另1例在超声引导下。

结果

16例仅接受肝囊肿疾病治疗的患者中,4例(25%)出现发热,3例,恶心呕吐1例;8例患者(50%)进行了腹腔引流,平均引流6-7天(范围4-11天),引流出116毫升血清血性液体。

结论

我们认为,选择适当的治疗方法必须基于对患者临床情况的准确评估以及囊肿病变的特征,如数量、大小和位置。这些数据使我们选择手术治疗而非严格的超声随访,并在无复发、降低生物学和经济成本方面取得最佳效果。

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