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嗜佩青霉,一种来自中国青海省的可产生新的灰黄霉素、金黄菌素和罗克福汀C的菌种。

Penicillium persicinum, a new griseofulvin, chrysogine and roquefortine C producing species from Qinghai Province, China.

作者信息

Wang Long, Zhou Han-Bai, Frisvad Jens C, Samson Robert A

机构信息

Systematic Mycology and Lichenology Lab., Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China.

出版信息

Antonie Van Leeuwenhoek. 2004 Aug;86(2):173-9. doi: 10.1023/B:ANTO.0000036140.86059.51.

DOI:10.1023/B:ANTO.0000036140.86059.51
PMID:15280651
Abstract

A unique Penicillium isolate from Chinese soil with terverticillate penicilli and ellipsoidal to cylindrical smooth-walled conidia, produces, in addition to the common metabolite ergosterol, copious amounts of an unknown peach-red pigment and the following secondary metabolites: griseofulvin, dechlorogriseofulvin, lichexanthone, roquefortine C, roquefortine D, chrysogine, 2-pyrovoylaminobenzamide, 2-acetyl-quinazolin-4(3H)-one. This isolate, CBS 111235, is described as Penicillium persicinum sp. nov., which belongs to subgenus Penicillium section Chrysogena but is morphologically similar to P. italicum. On the basis of the production of secondary metabolites it resembles P. griseofulvum and P. coprophilum. Sequence data using part of the beta-tubulin gene showed that it is phylogenetically related to P. chrysogenum and P. aethiopicum in section Chrysogena with which it shares both secondary metabolites and ability to grow at 37 degrees C.

摘要

从中国土壤中分离出的一种独特青霉菌株,其帚状枝呈轮生,分生孢子为椭圆形至圆柱形且壁光滑,除了产生常见代谢物麦角固醇外,还大量产生一种未知的桃红色色素以及以下次生代谢物:灰黄霉素、脱氯灰黄霉素、地衣黄质、罗克福汀C、罗克福汀D、金黄菌素、2-吡咯甲酰胺基苯甲酰胺、2-乙酰基喹唑啉-4(3H)-酮。该菌株,CBS 111235,被描述为新种桃色青霉(Penicillium persicinum sp. nov.),属于青霉属青霉亚属金产色组,但在形态上与意大利青霉相似。基于次生代谢物的产生情况,它类似于灰黄青霉和嗜粪青霉。使用部分β-微管蛋白基因的序列数据表明,它在系统发育上与金产色组的产黄青霉和埃塞俄比亚青霉相关,与它们共享次生代谢物以及在37℃下生长的能力。

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