Moser B
Fachkrankenhaus für Innere Medizin, Marienkrankenhaus Nassau.
Leber Magen Darm. 1992 Jul;22(4):150-4.
40 not selected elderly patients (average age 79.3 years were investigated with a oesophago-gastro-duodenoscopy (OGD). For premedication the patients got 5 mg Diazemuls R and 20 mg Buscopan R i.v. With 30 patients there was taken a blood-gas-analysis before premedication and before fiberendoscopy. ECG-registration was performed before OGD und during OGD with all patients. The premedication led to a reduction of the p02 on an average of 8.9%. The average pO2 did not decrease below the age-related value. In some cases there was a great difference. With a 86-year old woman the pO2 decreased about 25% after premedication and led to a severe hypoxaemiae. Only patients (12.5%) showed a few ventricular extrasystoles, there was no serious arrhythmia. After premedication the heart-rate rose over 100 heart-beats per minute up to maximal 137 beats/minute in 9 patients. If a low dose of Diazemuls R is used, there is no need to do the OGD in elderly patients without premedication. However, there should be the possibility to give a patient oxygen via nasal insufflation to prevent severe hypoxaemia which can occur in some cases. In general, monitoring is only necessary for patients with a higher risk.
40名未被挑选的老年患者(平均年龄79.3岁)接受了食管胃十二指肠镜检查(OGD)。术前用药时,患者静脉注射5毫克安定乳剂R和20毫克解痉灵R。30名患者在术前用药前和纤维内镜检查前进行了血气分析。所有患者在OGD前和OGD期间均进行了心电图记录。术前用药导致平均p02降低8.9%。平均pO2未降至与年龄相关的值以下。在某些情况下,差异很大。一名86岁女性在术前用药后pO2下降约25%,导致严重低氧血症。只有患者(12.5%)出现少数室性早搏,无严重心律失常。术前用药后,9名患者的心率升至每分钟100次以上,最高达137次/分钟。如果使用低剂量的安定乳剂R,老年患者在未进行术前用药的情况下无需进行OGD。然而,应该有可能通过鼻导管给患者吸氧,以防止在某些情况下可能发生的严重低氧血症。一般来说,只有高风险患者才需要监测。