Macalou D, Trueck S, Meuret P, Heck M, Vial F, Ouologuem S, Capdevila X, Virion J-M, Bouaziz H
*Department of Anesthesiology and Intensive Care, Central University Hospital, Nancy, France, the †Department of Anesthesiology and Intensive Care, Lapeyronie University Hospital, Montpellier, France, and the ‡Department of Epidemiology & Clinical Evaluation and Centre of Clinical Investigation, University Hospital, Nancy, France.
Anesth Analg. 2004 Jul;99(1):251-254. doi: 10.1213/01.ANE.0000121350.09915.84.
Femoral nerve block (FNB) does not consistently produce anesthesia of the obturator nerve. In this single-blind, randomized, controlled study we added a selective obturator nerve block (ONB) to FNB to analyze its influence on postoperative analgesia after total knee replacement (TKR). Before general anesthesia, 90 patients undergoing TKR received FNB (Group 1), FNB and selective ONB (Group 2), or placebo FNB (Group 3). Postoperative analgesia was further provided by morphine IV via patient-controlled analgesia. Analgesic efficacy and side effects were recorded in the first 6 h after surgery. Adductor strength decreased by 18% +/- 9% in Group 1 and by 78% +/- 22% in Group 2 (P < 0.0001). Total morphine consumption was reduced in Group 2 compared with Groups 1 and 3 (P < or = 0.0001). Patients in Group 2 reported lower pain scores than those in Groups 1 and 3 (P = 0.0003). The incidence of nausea was more frequent in Groups 1 and 3 (P = 0.01). We conclude that FNB does not produce complete anesthesia of the obturator nerve. Single-shot FNB does not provide additional benefits on pain at rest over opioids alone in the early postoperative period. The addition of an ONB to FNB improves postoperative analgesia after TKR.
股神经阻滞(FNB)并不能始终如一地产生闭孔神经麻醉。在这项单盲、随机、对照研究中,我们在FNB基础上增加了选择性闭孔神经阻滞(ONB),以分析其对全膝关节置换术(TKR)术后镇痛的影响。在全身麻醉前,90例行TKR的患者接受FNB(第1组)、FNB联合选择性ONB(第2组)或安慰剂FNB(第3组)。术后通过患者自控镇痛静脉注射吗啡进一步提供镇痛。记录术后前6小时的镇痛效果和副作用。第1组内收肌力量下降18%±9%,第2组下降78%±22%(P < 0.0001)。与第1组和第3组相比,第2组的吗啡总消耗量减少(P≤0.0001)。第2组患者的疼痛评分低于第1组和第3组(P = 0.0003)。第1组和第3组恶心发生率更高(P = 0.01)。我们得出结论,FNB不能产生完全的闭孔神经麻醉。单次FNB在术后早期对静息痛的缓解并不比单独使用阿片类药物有额外益处。FNB联合ONB可改善TKR术后镇痛效果。