钯催化苯炔的烯丙基炔基化反应：一种合成取代1-烯丙基-2-炔基苯的高效方法。
Palladium-catalyzed allylalkynylation of benzynes: a highly efficient route to substituted 1-allyl-2-alkynylbenzenes.
作者信息
Jeganmohan Masilamani, Cheng Chien-Hong
机构信息
Department of Chemistry, Tsing Hua University, Hsinchu, Taiwan 300, Republic of China.
出版信息
Org Lett. 2004 Aug 5;6(16):2821-4. doi: 10.1021/ol048891t.
PMID:15281778
Abstract
Benzynes, generated in situ from 2-(trimethylsilyl)aryl triflates and cesium fluoride, undergo allylalkynylation with allylic chlorides and alkynylstannanes in the presence of palladium catalyst to give 1-allyl-2-alkynylbenzenes in good to excellent yields. [reaction: see text]
摘要
由2-（三甲基甲硅烷基）芳基三氟甲磺酸酯和氟化铯原位生成的苯炔，在钯催化剂存在下与烯丙基氯和炔基锡烷发生烯丙基炔基化反应，以良好至优异的产率得到1-烯丙基-2-炔基苯。[反应：见正文]
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