Hsieh Chung-Bao, Chen Chung-Jueng, Chen Teng-Wei, Yu Jyh-Cherng, Shen Kuo-Liang, Chang Tzu-Ming, Liu Yao-Chi
Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China.
World J Gastroenterol. 2004 Aug 15;10(16):2394-6. doi: 10.3748/wjg.v10.i16.2394.
To investigate whether the non-invasive real-time Indocyanine green (ICG) clearance is a sensitive index of liver viability in patients before, during, and after liver transplantation.
Thirteen patients were studied, two before, three during, and eight following liver transplantation, with two patients suffering acute rejection. The conventional invasive ICG clearance test and ICG pulse spectrophotometry non-invasive real-time ICG clearance test were performed simultaneously. Using linear regression analysis we tested the correlation between these two methods. The transplantation condition of these patients and serum total bilirubin (T. Bil), alanine aminotransferase (ALT), and platelet count were also evaluated.
The correlation between these two methods was excellent (r(2)=0.977).
ICG pulse spectrophotometry clearance is a quick, non-invasive, and reliable liver function test in transplantation patients.
研究非侵入性实时吲哚菁绿(ICG)清除率是否为肝移植患者肝存活能力在肝移植术前、术中及术后的敏感指标。
对13例患者进行研究,其中2例为肝移植术前,3例为术中,8例为术后,2例发生急性排斥反应。同时进行传统的侵入性ICG清除率检测和ICG脉冲分光光度法非侵入性实时ICG清除率检测。采用线性回归分析检验这两种方法之间的相关性。还对这些患者的移植情况以及血清总胆红素(T. Bil)、丙氨酸转氨酶(ALT)和血小板计数进行了评估。
这两种方法之间的相关性极佳(r(2)=0.977)。
ICG脉冲分光光度法清除率是一种用于移植患者的快速、非侵入性且可靠的肝功能检测方法。