Druss Benjamin G, Marcus Steven C
Rollins School of Public Health, Emory University, USA.
Am J Psychiatry. 2004 Aug;161(8):1377-83. doi: 10.1176/appi.ajp.161.8.1377.
This study examined patterns of psychotropic medication use after the Sept. 11, 2001, terrorist attacks.
It drew from two large pharmacy data sets, one providing nationally representative aggregate projections for all U.S. prescriptions (156.9 million claims for psychotropic medications during the study period) and a second from the nation's largest pharmacy benefit management organization (36.4 million enrollees per month), 4.1% of whom had a prescription for a psychotropic medication during the study period. Analyses examined use of antidepressant, antipsychotic, anxiolytic, and hypnotic medications in the 12 weeks before and after Sept. 11, 2001, compared with the same weeks during 2000.
Nationally and in Washington, D.C., there was no evidence of an increase in overall prescriptions, new prescriptions, or daily doses for psychotropic medications. In New York City, there was an increase in the proportion of existing users with psychotropic dose increases in the weeks after the attacks (16.9% in 2001 versus 13.6% in 2000) but no significant increase in the rate of new psychotropic prescriptions.
For most of the nation, the distress associated with the terrorist attacks was not accompanied by a commensurate increase in the use of psychotropic medications. In New York City, there was a statistically significant but modest increase in the proportion of individuals with dose increases in their psychotropic medications.
本研究调查了2001年9月11日恐怖袭击后精神药物的使用模式。
该研究采用了两个大型药房数据集,一个提供全美具有代表性的所有美国处方的汇总预测数据(研究期间有1.569亿份精神药物索赔),另一个来自美国最大的药房福利管理组织(每月有3640万参保人),其中4.1%的参保人在研究期间有精神药物处方。分析比较了2001年9月11日前后12周与2000年同期抗抑郁药、抗精神病药、抗焦虑药和催眠药的使用情况。
在全国范围内以及在华盛顿特区,没有证据表明精神药物的总体处方量、新处方量或每日剂量有所增加。在纽约市,袭击发生后的几周内,现有精神药物使用者中剂量增加的比例有所上升(2001年为16.9%,2000年为13.6%),但新精神药物处方率没有显著增加。
对于美国大部分地区而言,与恐怖袭击相关的痛苦并没有伴随着精神药物使用量相应增加。在纽约市,精神药物剂量增加的个体比例有统计学上显著但适度的上升。