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激光与缝合神经吻合术

Laser vs. suture nerve anastomosis.

作者信息

Huang T C, Blanks R H, Berns M W, Crumley R L

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine Medical Center, Orange.

出版信息

Otolaryngol Head Neck Surg. 1992 Jul;107(1):14-20. doi: 10.1177/019459989210700103.

Abstract

The repair of injured or transected nerves is frequently encountered in head and neck surgery. Recently, CO2 lasers with milliwatt capability and micrometer spot sizes have been developed that may be used in nerve anastomosis. A comparative study was performed between microsuture and CO2 laser repair of transected sciatic nerves in rats. Nerve regeneration was measured in terms of morphology, electrophysiology, and function. Histologic studies revealed no difference in the size and number of regenerated axons, although there was less scar tissue formation at the anastomotic site with the laser repair. EMG and nerve conduction velocity were similar for the two repair methods. Functional recovery, as determined objectively using measurements of gait footprints, showed no difference between suture and laser repair. Laser-repaired nerves did have a higher dehiscence rate, although this problem can probably be prevented by splinting the rats postoperatively. However, laser repair was faster and simpler than suture repair and required less manipulation of the nerve. This study shows laser repair of peripheral nerves is possible with results comparable to conventional microsuture neurorrhaphy. Laser nerve anastomosis may be an effective alternative to suture nerve repair.

摘要

在头颈外科手术中,经常会遇到受伤或横断神经的修复问题。最近,已开发出具有毫瓦功率和微米光斑尺寸的二氧化碳激光,可用于神经吻合术。对大鼠坐骨神经横断伤采用显微缝合和二氧化碳激光修复进行了一项对比研究。从形态学、电生理学和功能方面对神经再生进行了测量。组织学研究显示,再生轴突的大小和数量没有差异,尽管激光修复的吻合部位瘢痕组织形成较少。两种修复方法的肌电图和神经传导速度相似。使用步态足迹测量客观确定的功能恢复情况显示,缝合修复和激光修复之间没有差异。激光修复的神经确实有较高的裂开率,不过这个问题或许可以通过术后对大鼠进行夹板固定来预防。然而,激光修复比缝合修复更快、更简单,且对神经的操作更少。这项研究表明,外周神经的激光修复是可行的,其结果与传统的显微缝合神经吻合术相当。激光神经吻合术可能是缝合神经修复的一种有效替代方法。

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