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大鼠坐骨神经显微外膜缝合、显微外膜缝合辅助二氧化碳激光以及单纯激光吻合的比较研究

Comparative study of microepineural suture, microepineural suture-aided CO2 laser, and laser only anastomoses in rat sciatic nerves.

作者信息

Sarlak A Y, Can C, Yüce E, Oba G

机构信息

Emergency Medicine Service of Cerrahpaşa Medical Faculty, Istanbul, Turkey.

出版信息

J Clin Laser Med Surg. 1994 Oct;12(5):273-6.

PMID:10150672
Abstract

The cut sciatic nerves of 33 rats were anastomosed by three different methods under the operation microscope; microepineural suture technique, CO2 laser technique, and laser-aided microepineural suture technique. On histologic examination at the end of 3 months postoperatively, in the CO2 laser and suture-aided CO2 laser groups, the degrees of inflammation, fibrosis, and Schwann cell vacuolar degeneration were significantly higher than in the microepineural suture anastomosis group. At the end of 3 months sciatic nerve function was absent in 3 of 11 rats anastomosed by only CO2 laser, however, sciatic nerve functions were found to be normal in the other two groups.

摘要

在手术显微镜下,采用三种不同方法对33只大鼠的坐骨神经切断处进行吻合;分别为显微神经外膜缝合技术、二氧化碳激光技术和激光辅助显微神经外膜缝合技术。术后3个月末进行组织学检查时,二氧化碳激光组和缝线辅助二氧化碳激光组的炎症、纤维化及施万细胞空泡变性程度显著高于显微神经外膜缝合吻合组。仅采用二氧化碳激光吻合的11只大鼠中,有3只在术后3个月末坐骨神经功能缺失,然而,其他两组的坐骨神经功能均正常。

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