Perdigão Fernanda Braga, Pierre-Filho Paulo de Tarso P, Natalino Renato José Mendonça, Caldato Roberto, Torigoe Marcelo, Cintra Maria Letícia
Department of Ophthalmology, State University of Campinas (UNICAMP), Campinas, SP, Brazil.
Rev Hosp Clin Fac Med Sao Paulo. 2004 Jun;59(3):135-7. doi: 10.1590/s0041-87812004000300008. Epub 2004 Jul 28.
Keratoacanthoma generally occurs on the skin; it is rarely found in the conjunctiva. A case of a 34-year-old woman with a rapidly growing conjunctival mass is reported. The tumor was excised with a safety margin to exclude squamous cell carcinoma. Histopathologically it was crateriform and consistent with atypical keratoacanthoma. There has been no recurrence in 2 years of follow-up. Conjunctival keratoacanthoma is rare; differential diagnosis of conventional squamous cell carcinoma and keratoacanthoma can be difficult. We recommend complete surgical excision and careful follow-up of crateriform squamous proliferations.
角化棘皮瘤通常发生于皮肤,很少见于结膜。本文报告了一例34岁女性结膜肿物迅速生长的病例。切除肿瘤时保留了安全切缘以排除鳞状细胞癌。组织病理学检查显示肿瘤呈火山口状,符合非典型角化棘皮瘤。随访2年无复发。结膜角化棘皮瘤罕见,常规鳞状细胞癌与角化棘皮瘤的鉴别诊断可能困难。我们建议对火山口状鳞状增生进行完整手术切除并仔细随访。