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2
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Keratoacanthoma (KA): An update and review.角化棘皮瘤(KA):更新与综述。
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Management of conjunctival malignant melanoma: a review and update.结膜恶性黑色素瘤的管理:综述与更新
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Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk.角化棘皮瘤的自发肿瘤消退是由Wnt/视黄酸信号串扰驱动的。
Nat Commun. 2014 Mar 26;5:3543. doi: 10.1038/ncomms4543.
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Cases with a spontaneous regression of an infiltrating non-crateriform keratoacanthoma and squamous cell carcinoma with a keratoacanthoma-like component.浸润性非火山口样角化棘皮瘤及具有角化棘皮瘤样成分的鳞状细胞癌自发消退的病例。
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Surgical versus medical treatment of ocular surface squamous neoplasia: a comparison of recurrences and complications.手术与药物治疗眼表鳞状上皮肿瘤:复发和并发症比较。
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Conjunctival keratoacanthoma.结膜角膜上皮瘤。
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Topical chemotherapy for ocular surface squamous neoplasia.眼表鳞状上皮肿瘤的局部化疗。
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结膜角化棘皮瘤的自发消退

Spontaneous regression of conjunctival keratoacanthoma.

作者信息

AlBayyat Ghada J, Venkateswaran Nandini, Arreaza Dan, Dubovy Sander R, Galor Anat, Karp Carol L

机构信息

Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA.

Florida Lions Ocular Pathology Laboratory, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USA.

出版信息

BMJ Case Rep. 2019 Jul 11;12(7):e228833. doi: 10.1136/bcr-2018-228833.

DOI:10.1136/bcr-2018-228833
PMID:31300607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6626488/
Abstract

An 83-year-old white man presented with a rapidly growing conjunctival mass in his left eye over the course of 1 month. While awaiting surgical intervention, the tumour underwent partial, spontaneous regression to half its original size. The lesion was ultimately excised with wide margins using a no-touch technique and application of cryotherapy to the corneal and conjunctival margins and scleral bed. Histopathological analysis revealed a conjunctival keratoacanthoma. To our knowledge, this is the first case documenting the partial, spontaneous regression of a conjunctival keratoacanthoma over a 5 week time course from the time of diagnosis to surgical excision.

摘要

一名83岁的白人男性在1个月内左眼出现迅速生长的结膜肿物。在等待手术干预期间,肿瘤部分自发消退至原来大小的一半。最终采用无接触技术,对角膜、结膜边缘及巩膜床进行冷冻治疗,将病变广泛切除。组织病理学分析显示为结膜角化棘皮瘤。据我们所知,这是首例记录结膜角化棘皮瘤从诊断到手术切除的5周时间内出现部分自发消退的病例。