局部神经冷却对迷走神经纤维传导的影响揭示了家兔的呼吸反射。

Effects of local nerve cooling on conduction in vagal fibres shed light upon respiratory reflexes in the rabbit.

作者信息

Patberg W R, Nijmeijer A, Schut J K, Versprille A, Zock J P, Zijlstra W G

机构信息

Department of Physiology, University of Groningen, The Netherlands.

出版信息

Pflugers Arch. 1992 Jun;421(2-3):280-2. doi: 10.1007/BF00374839.

DOI:10.1007/BF00374839

PMID:1528721

Abstract

In ten vagus nerves the effect of local cooling on the compound action potential was studied in the temperature range of 34 to 0 degrees C in spontaneously breathing, anaesthetized rabbits. The mean temperature at which the myelinated (A) fibres were completely blocked, was 10.2 +/- 2.4 degrees C (mean +/- S.D.). In nine nerves, local vagus cooling to 0 degrees C failed to block all non-myelinated (C) fibres. In one nerve, total blocking occurred at 2.0 degrees C. We conclude that in the rabbit, the earlier found increase in tonic activity of the diaphragm following lung inflation or deflation during bilateral local vagus cooling to a temperature between 8 and 0 degrees C is due to afferent impulses in vagal C fibres.

摘要

在自主呼吸的麻醉兔中，研究了10条迷走神经在34至0摄氏度温度范围内局部冷却对复合动作电位的影响。有髓鞘（A）纤维完全被阻断时的平均温度为10.2±2.4摄氏度（平均值±标准差）。在9条神经中，将局部迷走神经冷却至0摄氏度未能阻断所有无髓鞘（C）纤维。在1条神经中，在2.0摄氏度时出现完全阻断。我们得出结论，在兔中，先前发现的在双侧局部迷走神经冷却至8至0摄氏度之间的温度时，肺充气或放气后膈肌紧张性活动增加是由于迷走神经C纤维中的传入冲动所致。