Walsh Kathleen E, Berman Jennifer R
University of Wisconsin School of Medicine, Madison, Wisconsin, USA.
Drugs Aging. 2004;21(10):655-75. doi: 10.2165/00002512-200421100-00004.
Sexuality is one of the most important quality of life issues for both men and women. Sexual dysfunction is a highly prevalent, age-related and progressive problem. The various physiological and psychological changes that occur with aging can have a significant impact on sexual function. The complexity of female sexual dysfunction remains distinct from that of a man. Thus, we cannot approach female patients or their sexual function problems in a similar fashion to that of male patients. A woman's motivation and ability to find and respond to sexual stimuli is largely influenced by her emotional intimacy with her partner. Frequently, the emotional and relationship well-being a woman experiences contributes more to her sexual enjoyment than does her physiological response. However, it is imperative to assess for possible physiological barriers a woman may have which impede a healthy and satisfying sexual life. Therefore, a comprehensive approach, addressing both the physiological and psychological factors is instrumental to the evaluation of female patients with sexual complaints. After years of ardent research and recent therapeutic advances in male sexual dysfunction, researchers have begun addressing the intricacy of female sexual complaints. Studies involving both pre- and postmenopausal women have reported that most women do experience some type of sexual dysfunction during their lifetime. The sexual complaints women experience in their younger years may follow them into older adulthood, but often times change considerably because of various age-related changes. In an effort to assist researchers and clinicians in designing studies and implementing appropriate evaluation and treatment options for women with sexual complaints, a classification system for female sexual dysfunction has been designed. The four categories of female dysfunction include: hypoactive sexual desire disorder, sexual arousal disorder, orgasmic disorder and sexual pain disorders. Evaluation of women with sexual complaints should include a detailed psychological, social and medical history and thorough physical examination including a hormonal profile. Current treatment options are dependent on the diagnosis and include physical therapy, psychological counselling, hormonal supplements, medication changes and sexual devices. There has also been a burgeoning interest in investigational medications for female sexual dysfunction, from centrally acting (e.g. serotonin agonists) to peripheral, localised treatment (e.g. vasodilating creams). The area of female sexuality and sexual dysfunction has been undergoing important critical changes within the last 10 years. Researchers and clinicians are continuing to recognise the need to try and understand both the psychological and physiological aspects of the female sexual experience and how they influence one another.
性取向是男性和女性生活质量的最重要问题之一。性功能障碍是一个高度普遍、与年龄相关且逐渐发展的问题。随着年龄增长而发生的各种生理和心理变化会对性功能产生重大影响。女性性功能障碍的复杂性与男性仍有明显不同。因此,我们不能以与男性患者相同的方式来处理女性患者或她们的性功能问题。女性寻找和回应性刺激的动机及能力在很大程度上受其与伴侣情感亲密程度的影响。通常,女性所体验到的情感及关系的幸福感对其性愉悦的贡献比生理反应更大。然而,必须评估女性可能存在的妨碍健康和满意性生活的生理障碍。因此,一种综合考虑生理和心理因素的方法有助于对有性问题的女性患者进行评估。在对男性性功能障碍进行多年热烈研究及近期取得治疗进展之后,研究人员已开始着手处理女性性问题的复杂性。涉及绝经前和绝经后女性的研究报告称,大多数女性在其一生中确实会经历某种类型的性功能障碍。女性在年轻时经历的性问题可能会持续到老年,但通常会因各种与年龄相关的变化而有很大改变。为了帮助研究人员和临床医生设计研究,并为有性问题的女性实施适当的评估和治疗方案,已设计了一种女性性功能障碍分类系统。女性性功能障碍的四类包括:性欲减退障碍、性唤起障碍、性高潮障碍和性交疼痛障碍。对有性问题的女性进行评估应包括详细的心理、社会和病史,以及全面的体格检查,包括激素水平检测。当前的治疗方案取决于诊断结果,包括物理治疗、心理咨询、激素补充、药物调整和性器具。对于女性性功能障碍的研究性药物也有了迅速增长的兴趣,从作用于中枢的药物(如血清素激动剂)到外周局部治疗药物(如血管扩张乳膏)。在过去10年里,女性性取向和性功能障碍领域发生了重要的关键变化。研究人员和临床医生不断认识到需要尝试理解女性性体验的心理和生理方面以及它们如何相互影响。