Contreras Diego
Department of Neuroscience, University of Pennsylvania School of Medicine, 215 Stemmler Hall, Philadelphia, PA 19104-6074, USA.
Neural Netw. 2004 Jun-Jul;17(5-6):633-46. doi: 10.1016/j.neunet.2004.04.003.
Neocortical network behavior and neocortical function emerge from synaptic interactions among neurons with specific electrophysiological and morphological characteristics. The intrinsic electrophysiological properties of neurons define their firing patterns and their input-output functions with critical consequences for their functional properties within the network. Understanding the role played by the active non-linear properties caused by ionic conductances distributed in the soma and the dendrites is a critical step towards understanding cortical function. Here I present a brief description of electrophysiological and morphological characteristics of neocortical cells that allow their classification in categories. I review some examples of differences in functional properties among different electrophysiological cell classes in the visual cortex, as well as the role played by specific ionic conductances in defining firing and accommodation properties of neocortical neurons.
新皮层网络行为和新皮层功能源于具有特定电生理和形态特征的神经元之间的突触相互作用。神经元的内在电生理特性决定了它们的放电模式及其输入-输出功能,对它们在网络中的功能特性具有关键影响。了解由分布在胞体和树突中的离子电导引起的活性非线性特性所起的作用,是理解皮层功能的关键一步。在这里,我简要描述新皮层细胞的电生理和形态特征,以便对它们进行分类。我回顾了视觉皮层中不同电生理细胞类别的功能特性差异的一些例子,以及特定离子电导在定义新皮层神经元的放电和适应特性中所起的作用。