Sheiner Eyal, Levy Amalia, Mazor Moshe
Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel.
Eur J Obstet Gynecol Reprod Biol. 2004 Sep 10;116(1):43-7. doi: 10.1016/j.ejogrb.2004.02.006.
The study was aimed to identify risk factors and to elucidate pregnancy outcome following precipitate labor, i.e. expulsion of the fetus within less than 3 h of commencement of contractions.
A comparison of patients with and without precipitate labor, delivered during the years 1988-2002, was conducted. Patients who underwent cesarean deliveries were excluded from the analysis. A multiple logistic regression model, with backward elimination, was performed to investigate independent risk factors for precipitate labor.
The number of vaginal deliveries that occurred during the study period was 137,171. Of these, 99 were precipitate. Independent risk factors for precipitate labor, using a backward, stepwise multivariate analysis were: placental abruption (odds ratio (OR) = 30.9, 95% confidence interval (CI) 15.9-60.4, P < 0.001); fertility treatments (OR = 3.9, 95% CI 1.7-9.0, P = 0.002); chronic hypertension (OR = 3.1, 95% CI 1.2-7.8, P = 0.015); intrauterine growth restriction (IUGR) (OR = 2.9, 95% CI 1.2-6.8, P = 0.014); prostaglandin E2 induction (OR = 1.9, 95% CI 1.1-3.5, P = 0.045); birth weight < 2,500 g (OR = 1.8, 95% CI 1.1-3.1, P = 0.020); and nulliparity (OR = 1.7, 95% CI 1.1-2.6, P = 0.014). No significant differences were noted between the groups regarding perinatal complications such as meconium stained amniotic fluid, perinatal mortality and low Apgar scores. However, there were higher rates of maternal complications in the precipitate labor group such as cervical tears and grade 3 perineal tears (18.2% versus 0.3%, P < 0.001; and 2.0% versus 0.1%, P < 0.001, respectively), post-partum hemorrhage (13.1% versus 0.4%, P < 0.001); retained placenta (2.0% versus 0.5%, P = 0.02); the need for revision of uterine cavity and packed-cells transfusions (34.3% versus 4.9%, P < 0.001; and 11.1% versus 1.1%, P < 0.001, respectively) and prolonged hospitalization (27.6% versus 19.2%, P = 0.035) as compared to the controls.
Precipitate labor is associated with higher rates of maternal complications.
本研究旨在确定急产(即宫缩开始后不到3小时胎儿娩出)的危险因素,并阐明其妊娠结局。
对1988年至2002年期间分娩的有急产和无急产情况的患者进行比较。剖宫产患者被排除在分析之外。采用向后逐步消除法进行多因素逻辑回归模型分析,以研究急产的独立危险因素。
研究期间阴道分娩总数为137,171例,其中99例为急产。采用向后逐步多因素分析得出的急产独立危险因素有:胎盘早剥(比值比(OR)=30.9,95%置信区间(CI)15.9 - 60.4,P<0.001);辅助生殖治疗(OR = 3.9,95%CI 1.7 - 9.0,P = 0.002);慢性高血压(OR = 3.1,95%CI 1.2 - 7.8,P = 0.015);胎儿生长受限(IUGR)(OR = 2.9,95%CI 1.2 - 6.8,P = 0.014);前列腺素E2引产(OR = 1.9,95%CI 1.1 - 3.5,P = 0.045);出生体重<2500g(OR = 1.8,95%CI 1.1 - 3.1,P = 0.020);初产妇(OR = 1.7,95%CI 1.1 - 2.6,P = 0.014)。两组在围产期并发症如羊水粪染、围产儿死亡率及低Apgar评分方面无显著差异。然而,急产组产妇并发症发生率较高,如宫颈撕裂和Ⅲ度会阴撕裂(分别为18.2%对0.