Karthik Shishir, Srinivasan Arun K, Grayson Antony D, Jackson Mark, Sharpe David A C, Keenan Daniel J M, Bridgewater Ben, Fabri Brian M
Department of Cardiothoracic Surgery and Clinical Governance, The Cardiothoracic Centre-Liverpool, Thomas Drive, Liverpool L14 3PE, UK.
Eur J Cardiothorac Surg. 2004 Aug;26(2):318-22. doi: 10.1016/j.ejcts.2004.02.007.
To study the use of the additive and logistic European System for Cardiac Operative Risk Evaluation (EuroSCORE) to predict mortality following adult combined coronary artery bypass grafting (CABG) and valve surgery.
Data were collected prospectively, from all four centres providing adult cardiac surgery in the north west of England, on 1769 consecutive patients undergoing combined CABG and valve surgery between April 1997 and March 2002. Observed in-hospital mortality was compared to predicted mortality as determined by both additive and logistic EuroSCORE.
Observed mortality for simultaneous CABG and valve surgery was 8.7%, compared to 6.7% (additive) and 9.4% (logistic). Sixty-five percent of patients were classified as high-risk (additive EuroSCORE >5); the observed mortality was 11.5%, compared to 8.1% (additive) and 12.8% (logistic). Discrimination was similar in both systems as measured by the C statistic (additive 0.73, logistic 0.73).
The logistic EuroSCORE is more accurate at predicting mortality in simultaneous CABG and valve surgery, as the additive EuroSCORE significantly under-predicts in this high-risk group.
研究欧洲心脏手术风险评估系统(EuroSCORE)的相加法和逻辑回归法在预测成人冠状动脉旁路移植术(CABG)和瓣膜手术联合术后死亡率中的应用。
前瞻性收集了1997年4月至2002年3月间在英格兰西北部提供成人心脏手术的所有四个中心连续接受CABG和瓣膜手术联合治疗的1769例患者的数据。将观察到的院内死亡率与相加法和逻辑回归法EuroSCORE确定的预测死亡率进行比较。
CABG和瓣膜手术同期的观察死亡率为8.7%,相加法为6.7%,逻辑回归法为9.4%。65%的患者被归类为高危(相加法EuroSCORE>5);观察到的死亡率为11.5%,相加法为8.1%,逻辑回归法为12.8%。两种系统的判别能力相似,C统计量测量结果(相加法0.73,逻辑回归法0.73)。
逻辑回归法EuroSCORE在预测CABG和瓣膜手术同期死亡率方面更准确,因为相加法EuroSCORE在这个高危组中显著低估了死亡率。