Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, 250 Seongsan-ro, Seodaemun-gu, Seoul 120-752, Korea.
Yonsei Med J. 2010 May;51(3):326-31. doi: 10.3349/ymj.2010.51.3.326.
Combined coronary artery bypass (CAB) and valve surgery is one of the most challenging surgical procedures, but the operative results have improved over the years.
From 1989 through 2004, combined CAB and valve operations were performed in 125 patients. Mean age was 63 years, and 86 patients were male. Forty-six patients were diagnosed with coronary artery disease during preoperative evaluation for valvular heart disease (VHD). All patients underwent CAB, and one or more underwent valve replacement or repair (mitral: 54, aortic: 61, tricuspid: 3, DVR: 7) simultaneously.
Mean number of distal graft was 1.98 +/- 1.07, and LIMA was used in 68% of patients. Early mortality occurred in 6 patients (4.8%), and the causes were heart failure (4) and sepsis (2). Mean follow-up duration was 91.4 +/- 40.9 months (range: 47-245), and late mortality occurred in 4 patients. Kaplan Meier estimated survival rates at 1, 5, and 10 years were 94.4 %, 92.3%, and 89.9%, respectively.
Combined coronary and valve operations can be performed safely with optimal surgical results. Although the surgical mortality of coexisting coronary and VHD is higher than either isolated coronary or valvular operations, it may not affect the long-term survival.
冠状动脉旁路移植术(CAB)与瓣膜手术联合是最具挑战性的手术之一,但近年来手术效果有所改善。
1989 年至 2004 年,共有 125 例患者接受了 CAB 和瓣膜联合手术。平均年龄为 63 岁,86 例为男性。46 例患者在术前评估瓣膜性心脏病(VHD)时被诊断为冠心病。所有患者均接受 CAB 治疗,1 例或 1 例以上患者同时接受瓣膜置换或修复(二尖瓣:54 例,主动脉瓣:61 例,三尖瓣:3 例,DVR:7 例)。
平均远端移植物数量为 1.98±1.07,68%的患者使用了左乳内动脉。6 例(4.8%)患者发生早期死亡,原因是心力衰竭(4 例)和脓毒症(2 例)。平均随访时间为 91.4±40.9 个月(范围:47-245),4 例患者发生晚期死亡。Kaplan-Meier 估计 1、5 和 10 年的生存率分别为 94.4%、92.3%和 89.9%。
联合冠状动脉和瓣膜手术可以安全进行,并获得理想的手术效果。尽管同时存在冠心病和 VHD 的手术死亡率高于单独的冠状动脉或瓣膜手术,但这可能不会影响长期生存率。