Cazacu Andreea C, Demmler Gail J, Neuman Mark A, Forbes Betty A, Chung Sooyoung, Greer Jewel, Alvarez Ana E, Williams Robin, Bartholoma Nadine Y
Department of Pediatrics, Baylor College of Meidcine, Houston, TX 77030, USA.
J Clin Microbiol. 2004 Aug;42(8):3661-4. doi: 10.1128/JCM.42.8.3661-3664.2004.
The performance of a new rapid lateral-flow chromatographic membrane immunoassay test kit for detection of influenza virus was evaluated and compared to that of viral culture in respiratory secretions collected from 400 adults and children seen at three large university hospitals during the recent 2003 influenza season. The rapid test provided results in 15 min, with excellent overall performance statistics (sensitivity, 94.4%; specificity, 100%; positive predictive value, 100%; negative predictive value, 97.5%). Both influenza A and B type viruses were reliably detected, with no significant difference in performance statistics noted by influenza virus type or by the center performing the test.
对一种用于检测流感病毒的新型快速侧向流动色谱膜免疫分析检测试剂盒的性能进行了评估,并与在最近的2003年流感季节从三家大型大学医院就诊的400名成人和儿童收集的呼吸道分泌物中的病毒培养结果进行了比较。快速检测在15分钟内得出结果,总体性能统计数据出色(敏感性为94.4%;特异性为100%;阳性预测值为100%;阴性预测值为97.5%)。甲型和乙型流感病毒均能可靠检测,按流感病毒类型或进行检测的中心划分,性能统计数据无显著差异。