Pieniazek Piotr, Musialek Piotr, Motyl Rafał, Kablak-Ziembicka Anna, Kadzielski Andrzej, Przewlocki Tadeusz, Zmudka Krzysztof, Tracz Wiesława
Department of Cardiac and Vascular Diseases, Jagiellonian University, Krakow, Poland.
J Endovasc Ther. 2004 Aug;11(4):511-6. doi: 10.1583/04-1203.1.
To report the use of the Parodi Anti-Emboli System (PAES) for cerebral protection during emergent vertebral artery recanalization.
A 56-year-old chimney sweep was referred with recurrent episodes of vertigo and gait ataxia. Left vertebral artery (LVA) flow was barely detectable on duplex Doppler, and brain computed tomography revealed a small infarct in the posterior inferior cerebellar artery territory. Angiography showed subtotal ostial stenosis of the LVA with poor distal flow and possible thrombus. Due to a high risk of distal embolization with percutaneous treatment, anticoagulation was initiated, and the lesion was to be re-evaluated in 2 to 3 weeks. However, 2 days later, the patient developed severe, aggravating headache, gait and left-limb ataxia, horizontal nystagmus, and vomiting. Emergent angiography showed a total ostial LVA occlusion. The PAES was employed to elicit a temporary subclavian steal during percutaneous LVA recanalization, thus protecting the brain from embolization. The ostial LVA was successfully recanalized and stented, with immediate symptom cessation.
The PAES can be successfully applied in the subclavian artery to prevent distal embolization during emergent vertebral artery recanalization. Since a significant proportion of vertebral strokes are embolic, PAES may play a novel role in the treatment of acute cerebellar stroke.
报告在急诊椎动脉再通术中使用帕罗迪抗栓系统(PAES)进行脑保护。
一名56岁的烟囱清洁工因反复出现眩晕和步态共济失调前来就诊。双功多普勒检查几乎检测不到左椎动脉(LVA)血流,脑部计算机断层扫描显示小脑后下动脉区域有一个小梗死灶。血管造影显示LVA开口处次全狭窄,远端血流不佳且可能有血栓形成。由于经皮治疗存在远端栓塞的高风险,开始进行抗凝治疗,并计划在2至3周后对病变进行重新评估。然而,两天后,患者出现严重且逐渐加重的头痛、步态和左肢共济失调、水平性眼球震颤及呕吐。急诊血管造影显示LVA开口处完全闭塞。在经皮LVA再通术中使用PAES诱发暂时性锁骨下窃血,从而保护脑部免受栓塞。LVA开口处成功再通并置入支架,症状立即消失。
PAES可成功应用于锁骨下动脉,以防止急诊椎动脉再通术中的远端栓塞。由于相当一部分椎动脉卒中是栓塞性的,PAES可能在急性小脑卒中的治疗中发挥新作用。