Maciejewski Damian, Tekieli Łukasz, Kabłak-Ziembicka Anna, Paluszek Piotr, Trystuła Mariusz, Wójcik-Pędziwiatr Magdalena, Machnik Roman, Pieniążek Piotr
Department of Interventional Cardiology, Institute of Cardiology, Medical College, Jagiellonian University, John Paul II Hospital, Krakow, Poland.
Department of Vascular Surgery and Endovascular Interventions, Medical College, Jagiellonian University, John Paul II Hospital, Krakow, Poland.
Postepy Kardiol Interwencyjnej. 2015;11(1):32-6. doi: 10.5114/pwki.2015.49182. Epub 2015 Mar 6.
Symptomatic severe vertebral artery (VA) stenosis may be treated safely with stent supported angioplasty via femoral access. There is limited clinical data on transradial approach for VA angioplasty in case of peripheral artery disease.
To evaluate the safety and efficacy of transradial angioplasty of symptomatic VA stenosis.
Fifteen patients (age 66 ±7.4 years, 73% men, with VA > 80% stenosis, 11 right-side, all symptomatic from posterior circulation (history of stroke, TIA, or chronic ischaemia symptoms)) with peripheral artery disease (PAD) or unsuccessful attempt via femoral approach were scheduled for VA angioplasty by radial access. Clinical and duplex ultrasound (DUS) follow-up were performed before discharge and 1, 12, and 24 months after VA angioplasty.
The technical success rate was 100%. In all cases VA angioplasty was performed with the use of single balloon-mounted stent (9 bare metal stents, 6 drug-eluting stents). The mean NASCET VA stenosis was reduced from 85.3% to 5.3% (p < 0.001). No periprocedural death, stroke, myocardial infarction, or transient ischaemic attack occurred. During 24-months follow-up, in 12 of 15 patients chronic ischaemia symptoms release was observed, and no new acute ischaemic neurological symptoms were diagnosed in all patients. One patient died 20 months after intervention from unknown causes. There was one symptomatic borderline VA in-stent stenosis 12 months after angioplasty.
Transradial VA stenting may be a very effective and safe procedure, and it may constitute an alternative to the femoral approach in patients with symptomatic VA stenosis.
有症状的严重椎动脉(VA)狭窄可通过经股动脉途径的支架辅助血管成形术安全治疗。对于外周动脉疾病患者行VA血管成形术的经桡动脉途径,临床数据有限。
评估有症状的VA狭窄经桡动脉血管成形术的安全性和有效性。
15例患者(年龄66±7.4岁,73%为男性,VA狭窄>80%,11例为右侧,均有后循环症状(中风史、短暂性脑缺血发作或慢性缺血症状))患有外周动脉疾病(PAD)或经股动脉途径尝试失败,计划行经桡动脉途径的VA血管成形术。在出院前以及VA血管成形术后1个月、12个月和24个月进行临床和双功超声(DUS)随访。
技术成功率为100%。所有病例均使用单枚球囊扩张支架进行VA血管成形术(9枚裸金属支架,6枚药物洗脱支架)。平均北美症状性颈动脉内膜切除试验(NASCET)VA狭窄率从85.3%降至5.3%(p<0.001)。未发生围手术期死亡、中风、心肌梗死或短暂性脑缺血发作。在24个月的随访期间,15例患者中有12例观察到慢性缺血症状缓解,所有患者均未诊断出新的急性缺血性神经症状。1例患者在干预20个月后因不明原因死亡。血管成形术后12个月有1例有症状的临界VA支架内狭窄。
经桡动脉VA支架置入术可能是一种非常有效且安全的手术,对于有症状的VA狭窄患者,它可能是经股动脉途径的一种替代方法。