Holt Stephen, Donaldson Helen, Hazlehurst Geoffrey, Varghese Zac, Contreras Marcela, Kingdon Edward, Sweny Paul, Burns Aine
Renal Unit, Brighton and Sussex University Hospitals, Royal Sussex County Hospital, Brighton BN2 5BE, UK.
Nephrol Dial Transplant. 2004 Sep;19(9):2403-6. doi: 10.1093/ndt/gfh333.
Many renal transplant centres now try to avoid blood transfusion prior to renal transplantation, to avoid alloimmunization due to antibody production against donor antigens usually present on contaminating white cells. Post- or peri-operative transfusions are usually not considered to present problems, since the patient is heavily immunosuppressed. We present a patient who suffered a rare transfusion reaction, that we believe may have initiated a severe vascular rejection of a kidney transplant, probably mediated by Kidd blood group antigens.