Dogra P N, Ansari M S, Gupta N P, Tandon S
Department of Urology, All India Institute of Medical Sciences, New Delhi, India.
Urology. 2004 Aug;64(2):232-5; discussion 235-6. doi: 10.1016/j.urology.2004.03.050.
To determine the safety and efficacy of holmium laser core-through urethrotomy (HolCTU) for the treatment of post-traumatic obliterative stricture of the urethra.
From June 2002 to March 2003, 29 men underwent the core-through procedure. All the patients had obliterative strictures of the bulbomembranous urethra. The length of the stricture was 2.5 cm or less, with good alignment between the two urethral ends. The holmium laser was used to vaporize the obliterative fibrotic tissue. The procedure was guided by a metal sound introduced through the suprapubic tract. Catheter removal and voiding cystourethrography were done at 6 weeks after the procedure and urethroscopy 1 month after catheter removal.
At a mean follow-up of 15 months (range 10 to 19), the results were excellent in 19 (65.51%) of 29 patients. Nine (31.03%) had acceptable results; these patients failed to maintain good flow after HolCTU and required internal urethrotomy/endoscopic dilation once or twice for stabilization (maximal flow rate 15 mL/s or greater). Failure was seen in 1 patient (3.44%) who had recurrent obstruction despite repeated internal urethrotomy and finally required formal transpubic urethroplasty. The mean operating time was 40 minutes (range 30 to 90), with mean hospital stay of 8 hours (range 6 to 48). No perioperative complications occurred, except in 1 patient who developed small extravasation of fluid locally. All the patients were continent, and potency status was unaffected by HolCTU.
HolCTU is a safe and simple treatment for obliterative urethral strictures. The procedure is less morbid than open repair with a slightly greater failure rate.
确定钬激光经尿道核心切开术(HolCTU)治疗创伤后尿道闭锁性狭窄的安全性和有效性。
2002年6月至2003年3月,29名男性接受了经尿道核心切开手术。所有患者均患有球膜部尿道闭锁性狭窄。狭窄长度为2.5厘米或更短,尿道两端对合良好。使用钬激光汽化闭锁性纤维化组织。该手术由经耻骨上途径插入的金属探子引导。术后6周拔除导尿管并进行排尿性膀胱尿道造影,拔除导尿管1个月后进行尿道镜检查。
平均随访15个月(范围10至19个月),29例患者中有19例(65.51%)效果极佳。9例(31.03%)效果尚可;这些患者在HolCTU后未能维持良好的尿流,需要进行一到两次内切开术/内镜扩张以稳定尿流(最大尿流率15毫升/秒或更高)。1例患者(3.44%)失败,尽管反复进行内切开术仍出现复发性梗阻,最终需要进行正式的耻骨上尿道成形术。平均手术时间为40分钟(范围30至90分钟),平均住院时间为8小时(范围6至48小时)。除1例患者局部出现少量液体外渗外,未发生围手术期并发症。所有患者均能自主排尿,性功能状态不受HolCTU影响。
HolCTU是治疗闭锁性尿道狭窄的一种安全、简单的方法。该手术比开放修复的创伤性小,但失败率略高。