Dogra P N, Aron M, Rajeev T P
Department of Urology, All India Institute of Medical Sciences, New Delhi.
J Urol. 1999 Jan;161(1):81-4. doi: 10.1016/s0022-5347(01)62071-8.
We studied the safety and efficacy of core through urethrotomy with the neodymium (Nd):YAG laser for posttraumatic obliterative strictures of the bulbomembranous urethra.
Eight patients a mean of 27.5 years old with posttraumatic (motor vehicle accidents) obliterative strictures of the bulbomembranous urethra were treated from May to December 1997. Laser treatment selection criteria were stricture length 2.0 cm. or less, good alignment between the urethral ends and no history of rectal injury or erectile dysfunction. All patients underwent core through urethrotomy with the Nd:YAG contact laser delivered with the 600 micro bare fiber at 15 to 25 W. The urethrotomy was guided only by a metal sound introduced through the suprapubic tract.
Blood loss was negligible and excellent visualization was maintained throughout the procedure. Operating time ranged from 45 to 70 minutes. There were no perioperative complications. Hospital stay was 24 hours in the first case and 6 to 8 hours in subsequent cases. All patients returned to work within 5 days. Urethroscopy was performed 4 and 12 weeks after catheter removal in all patients. Only 1 patient required repeat internal urethrotomy. Voiding cystourethrography revealed a stricture-free urethra in 7 cases. At last followup 7 to 14 months (mean 10.25) after the procedure mean maximum flow rate was 18.6 ml. per second (range 16.5 to 22.4) in the patients who were stricture-free and 11.8 ml. per second in 1 with recurrent stricture.
Core through urethrotomy with the contact Nd:YAG laser seems to be a safe and effective treatment option for select strictures. The hospital stay is remarkably short and complications are negligible. Re-stricture rates are likely to be low but more experience and longer follow-up are needed.
我们研究了使用钕(Nd):YAG激光经尿道核心切开术治疗创伤后球膜部尿道闭塞性狭窄的安全性和有效性。
1997年5月至12月,对8例平均年龄27.5岁的创伤后(机动车事故)球膜部尿道闭塞性狭窄患者进行了治疗。激光治疗选择标准为狭窄长度2.0厘米或更短、尿道两端对合良好且无直肠损伤或勃起功能障碍病史。所有患者均使用600微米裸光纤以15至25瓦的功率通过Nd:YAG接触式激光进行经尿道核心切开术。尿道切开术仅通过经耻骨上途径插入的金属探子引导。
术中失血可忽略不计,整个手术过程中视野清晰。手术时间为45至70分钟。无围手术期并发症。第一例患者住院时间为24小时,后续患者为6至8小时。所有患者均在5天内恢复工作。所有患者在拔除导尿管后4周和12周进行了尿道镜检查。仅1例患者需要再次进行尿道内切开术。排尿性膀胱尿道造影显示7例患者尿道无狭窄。在术后7至14个月(平均10.25个月)的最后随访中,无狭窄患者的平均最大尿流率为每秒18.6毫升(范围为16.5至22.4),1例复发性狭窄患者的平均最大尿流率为每秒11.8毫升。
使用接触式Nd:YAG激光经尿道核心切开术似乎是治疗特定狭窄的一种安全有效的选择。住院时间明显较短,并发症可忽略不计。再狭窄率可能较低,但需要更多经验和更长时间的随访。