Kowalewski Janusz, Dancewicz Maciej, Pepliński Janusz, Sir Jan
Z Katedry i Kliniki Chirurgii Klatki Piersiowej i Nowotworów AM w Bydgoszczy.
Pneumonol Alergol Pol. 2003;71(11-12):521-6.
Histological examination was performed on 93 pulmonary nodules resected in 90 patients with known malignancy. The diameters of the coin lesions on CT scan were 3-10 mm in 42 cases and 11-30 mm in 51 cases. The most common sources of the previous malignancy were: large bowel (20), breast (14), uterus (12), kidney (11) and larynx (7). In 84 cases the nodules were radically resected through "wedge" resection and in 9 cases lobectomy was performed. Most frequently, coin lesion was caused by metastases of known malignancy (in 69.9%), pulmonary fibrosis (in 11.8%) and by primary lung cancer (in 7.5%). In general, pulmonary nodules were found malignant in 78.5% and benign in 21.5% of the cases. In the subgroup of coin lesions of diameter between 11 and 30 mm malignancy was noted in 94.1%--significantly more frequently than in subgroup of diameter between 3 and 10 mm (59.5%). No significant correlation was found between histological type of pulmonary nodules (malignant or benign) and the type of primary malignancy as well as the time from the treatment of primary malignancy to the detection of the coin lesion.
对90例已知患有恶性肿瘤的患者切除的93个肺结节进行了组织学检查。CT扫描上的类圆形病灶直径在42例中为3 - 10毫米,在51例中为11 - 30毫米。既往恶性肿瘤最常见的来源是:大肠(20例)、乳腺(14例)、子宫(12例)、肾(11例)和喉(7例)。84例结节通过“楔形”切除术根治性切除,9例行肺叶切除术。最常见的情况是,类圆形病灶由已知恶性肿瘤转移引起(69.9%)、肺纤维化(11.8%)和原发性肺癌(7.5%)。总体而言,78.5%的肺结节被发现为恶性,21.5%为良性。在直径为11至30毫米的类圆形病灶亚组中,94.1%被发现为恶性——明显比直径为3至10毫米的亚组(59.5%)更常见。未发现肺结节的组织学类型(恶性或良性)与原发性恶性肿瘤的类型以及从原发性恶性肿瘤治疗到发现类圆形病灶的时间之间存在显著相关性。