Lillington G A
Stanford University School of Medicine, California, USA.
Postgrad Med. 1997 Mar;101(3):145-50. doi: 10.3810/pgm.1997.03.177.
Although each case must be considered individually, there are several basic principles of management in cases of solitary pulmonary nodules: Every nodule must be regarded as potentially malignant until proven otherwise. Malignant nodules should be resected unless the procedure is contraindicated because of an unacceptably high surgical risk or evidence of metastasis. Resection of a benign nodule rarely benefits the patient and carries a small but significant mortality risk. Ruling out malignancy by less-invasive means than thoracotomy is desirable wherever possible. A management decision should be reached with reasonable promptness once a solitary pulmonary nodule has been detected. Under certain circumstances, a decision to observe the nodule for a period of time with serial chest films may be appropriate, but this must be a considered approach and not a "default" position.
虽然每个病例都必须单独考虑,但孤立性肺结节病例的管理有几个基本原则:在证明并非如此之前,每个结节都必须被视为潜在恶性。除非由于手术风险过高或有转移证据而禁忌手术,否则恶性结节应予以切除。切除良性结节很少能使患者受益,且有小但显著的死亡风险。只要有可能,应通过比开胸手术侵入性更小的方法排除恶性肿瘤。一旦发现孤立性肺结节,应合理迅速地做出管理决策。在某些情况下,决定通过连续胸部X光片观察结节一段时间可能是合适的,但这必须是经过深思熟虑的方法,而不是“默认”立场。