Lee Victor K M, McCaughan Brian C, Scolyer Richard A
Department of Anatomical Pathology, Singapore General Hospital, Singapore.
Int J Surg Pathol. 2004 Jul;12(3):287-92. doi: 10.1177/106689690401200313.
Although uncommon, it is well recognized that salivary gland-type tumors can occur as primary lung tumors, probably arising from minor salivary-type glands lining the bronchial tree. Polymorphous low-grade adenocarcinoma (PLGA) is a rare tumor that usually originates from oral minor salivary glands. There are only 2 reported cases showing metastasis to the lung; however, a primary lung tumor has not been reported so far. In this report we describe the clinical and pathological features of another case of PLGA involving the lung, but in a patient with no evidence of a previous oropharyngeal primary. While our case probably represents another example of metastatic PLGA to the lung, to our knowledge, it is the first description of a PLGA involving the lung in the absence of a history of a previous primary oral salivary gland tumor.
虽然罕见,但唾液腺型肿瘤可作为原发性肺肿瘤出现,这一点已得到充分认识,其可能起源于支气管树内衬的小唾液腺样腺体。多形性低度腺癌(PLGA)是一种罕见肿瘤,通常起源于口腔小唾液腺。仅有2例报告显示其转移至肺;然而,迄今为止尚未有原发性肺肿瘤的报告。在本报告中,我们描述了另一例累及肺部的PLGA的临床和病理特征,但该患者无先前口咽原发性肿瘤的证据。虽然我们的病例可能代表了PLGA转移至肺的另一个例子,但据我们所知,这是首次描述在无先前原发性口腔唾液腺肿瘤病史的情况下累及肺部的PLGA。