Zarzecki Miłosz, Chudek Jerzy, Kułach Andrzej, Hołowiecka Aleksandra, Kania Magdalena, Kopeć Paulina, Kukla Małgorzata, Machała Ludwina, Pyda Michał, Rozmus Wioletta, Szpak Sylwia, Wiecek Andrzej
Z Katedry i Kliniki Nefrologii, Endokrynologii i Chorób Przemiany Materii Slaskiej Akademii Medycznej w Katowicach.
Wiad Lek. 2004;57(3-4):145-50.
The aim of this study was to evaluate the causes of chronic renal failure and clinical status of patients during the onset of hemodialysis therapy in Upper Silesian region. Medical documentation and questionnaires of 175 patients initiating hemodialysis therapy from November 1999 to October 2000 were analyzed. Concentrations of creatinine, calcium, phosphorus in serum, hemoglobin in blood, concomitance of hypertension, frequency of uremic symptoms, HBV and HCV infections, and occurrence of mature arterio-venous fistula before the first hemodialysis were assessed. The main causes of end stage kidney disease were: chronic glomerulonephritis (29%), diabetic nephropathy (27%), polycystic kidney disease (15%), interstitial (11%) and hypertensive (9%) nephropathy. The first contact with nephrologist for 30% of patients was the admission for the initiation of renal replacement therapy. 33% of patients were treated due to chronic renal failure shorter than 1 year. Only 53% of patients had matured arterio-venous fistula during the first hemodialysis session. Anemia, hyperphosphatemia (>1.7 mmol/l) and arterial hypertension were found in 87%, 49.5% and 82% of patients starting hemodialysis therapy, respectively. The main symptoms of chronic uremia were weakness, pruritus, swelling, nausea and insomnia.
Most of patients with chronic renal failure is referred to the nephrologists at the advanced stage of the disease. It is especially true for patients with diabetic nephropathy.
本研究的目的是评估上西里西亚地区血液透析治疗开始时慢性肾衰竭的病因及患者的临床状况。分析了1999年11月至2000年10月开始血液透析治疗的175例患者的医疗记录和问卷。评估了血清肌酐、钙、磷浓度,血液中的血红蛋白,高血压的合并情况,尿毒症症状的发生频率,乙肝和丙肝感染情况,以及首次血液透析前成熟动静脉内瘘的出现情况。终末期肾病的主要病因是:慢性肾小球肾炎(29%)、糖尿病肾病(27%)、多囊肾病(15%)、间质性(11%)和高血压(9%)肾病。30%的患者首次接触肾病科医生是因开始肾脏替代治疗而入院。33%的患者因慢性肾衰竭病程短于1年接受治疗。只有53%的患者在首次血液透析时已有成熟的动静脉内瘘。开始血液透析治疗的患者中,分别有87%、49.5%和82%存在贫血、高磷血症(>1.7 mmol/L)和动脉高血压。慢性尿毒症的主要症状是乏力、瘙痒、水肿、恶心和失眠。
大多数慢性肾衰竭患者在疾病晚期才转诊至肾病科医生处。糖尿病肾病患者尤其如此。