多排螺旋CT引导下经动脉化疗栓塞术治疗大肝癌时根据肿瘤血供调整碘油剂量
Adjustment of lipiodol dose according to tumor blood supply during transcatheter arterial chemoembolization for large hepatocellular carcinoma by multidetector helical CT.
作者信息
Cheng Hong-Yan, Shou Yi, Wang Xiang, Xu Ai-Min, Chen Dong, Jia Yu-Chen
机构信息
Department of Radiology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China.
出版信息
World J Gastroenterol. 2004 Sep 15;10(18):2753-5. doi: 10.3748/wjg.v10.i18.2753.
AIM
To work out an individualized lipiodol dose in transcatheter arterial chemoembolization (TACE) for large hepatocellular carcinoma (HCC) according to its blood supply evaluated by CT.
METHODS
One hundred patients with large HCC (more than 8 cm in diameter) were studied by multidetector helical CT. Patterns of blood supply of HCC were divided into sufficient blood supply, poor blood supply, mixed blood supply and arteriovenous (A-V) shunt. The dose of ultra-fluid lipiodol was determined by diameter and blood supply type of HCC. Patients were divided into two groups (50 cases each): lipiodol perfusion group and iodized oil perfusion group according to tumor diameter and the blood supply type of tumor.
RESULTS
The confirmation and effective rates were 82%, 84% in the first group and 36%, 46% in the second group (P<0.01).
CONCLUSION
A relatively individualized lipiodol dose may be determined according to the blood supply pattern and the tumor diameter by CT imaging.
目的
根据CT评估的大肝细胞癌（HCC）血供情况，制定经动脉化疗栓塞术（TACE）中个体化的碘油剂量。
方法
采用多排螺旋CT对100例直径大于8cm的大HCC患者进行研究。HCC的血供模式分为血供丰富、血供差、混合血供和动静脉（A-V）分流。超液化碘油剂量根据HCC的直径和血供类型确定。根据肿瘤直径和肿瘤血供类型将患者分为两组（每组50例）：碘油灌注组和碘化油灌注组。
结果
第一组的确诊率和有效率分别为82%、84%，第二组分别为36%、46%（P<0.01）。
结论
通过CT成像可根据血供模式和肿瘤直径确定相对个体化的碘油剂量。
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