中国肥胖儿童的血脂谱

Serum lipid profile in obese children in China.

作者信息

Li Shilian, Liu Xiaolan, Okada Tomoo, Iwata Fujihiko, Hara Mitsuhiko, Harada Kensuke

机构信息

Beijing Children's Hospital Affiliated with Capital University of Medical Sciences, Beijing, People's Republic of China.

出版信息

Pediatr Int. 2004 Aug;46(4):425-8. doi: 10.1111/j.1442-200x.2004.01908.x.

DOI:10.1111/j.1442-200x.2004.01908.x

PMID:15310307

Abstract

BACKGROUND

The aim of the present study was to examine the serum lipid profile in obese Chinese children, their serum lipid and apolipoprotein A-I (apoA-I) and B (apoB) levels were examined.

METHODS

The subjects were 153 patients (109 male and 44 female) aged 4-16 years with obesity, who attended the outpatient clinic of Beijing Children's Hospital. Percentage bodyweight (%BW) ([(bodyweight - standard weight)/standard weight]x 100) were obtained. Skinfold thickness and hip and waist circumference were measured. Percentage body fat (%BF) was estimated by bioelectrical impedance analyzer. Serum total cholesterol (TC), high density lipoprotein cholesterol (HDLC), triglyceride (TG), apoA-I and apoB levels were also measured.

RESULTS

TC showed an acceptable level in 86.8% of obese children. The prevalence of high TC levels (3.3%) or high LDLC levels (6.0%) was rather low. The HDLC level was reduced in 31.3% of obese children. Anthropometric variables had no linear relationship to TC, HDLC, TG, LDLC, apoA-I or apoB, but in the older age group (over 10 years old) %BW and %BF showed a weak correlation with HDLC (r = -0.202, r = -0.211, respectively).

CONCLUSION

In obese Chinese children, HDLC as well as TC levels should be examined in order to assess coronary risk.

摘要

背景

本研究旨在检测肥胖中国儿童的血脂谱，检测他们的血脂、载脂蛋白A-I（apoA-I）和载脂蛋白B（apoB）水平。

方法

研究对象为153例4至16岁的肥胖门诊患儿（男109例，女44例），来自北京儿童医院。计算体重百分比（%BW）[（体重-标准体重）/标准体重×100]，测量皮褶厚度、臀围和腰围，用生物电阻抗分析仪估算体脂百分比（%BF），同时检测血清总胆固醇（TC）、高密度脂蛋白胆固醇（HDLC）、甘油三酯（TG）、apoA-I和apoB水平。

结果

86.8%的肥胖儿童TC水平正常，高TC水平（3.3%）或高低密度脂蛋白胆固醇（LDLC）水平（6.0%）的患病率较低，31.3%的肥胖儿童HDLC水平降低。人体测量学变量与TC、HDLC、TG、LDLC、apoA-I或apoB无线性关系，但在年龄较大组（10岁以上），%BW和%BF与HDLC呈弱相关（分别为r = -0.202，r = -0.211）。