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DisProt:蛋白质无序数据库。

DisProt: a database of protein disorder.

作者信息

Vucetic Slobodan, Obradovic Zoran, Vacic Vladimir, Radivojac Predrag, Peng Kang, Iakoucheva Lilia M, Cortese Marc S, Lawson J David, Brown Celeste J, Sikes Jason G, Newton Crystal D, Dunker A Keith

机构信息

Center for Information Science and Technology, Temple University Philadelphia, PA 19122, USA.

出版信息

Bioinformatics. 2005 Jan 1;21(1):137-40. doi: 10.1093/bioinformatics/bth476. Epub 2004 Aug 13.

Abstract

UNLABELLED

The Database of Protein Disorder (DisProt) is a curated database that provides structure and function information about proteins that lack a fixed three-dimensional (3D) structure under putatively native conditions, either in their entirety or in part. Starting from the central premise that intrinsic disorder is an important structural class of protein and in order to meet the increasing interest thereof, DisProt is aimed at becoming a central repository of disorder-related information. For each disordered protein, the database includes the name of the protein, various aliases, accession codes, amino acid sequence, location of the disordered region(s), and methods used for structural (disorder) characterization. If applicable, most entries also list the biological function(s) of each disordered region, how each region of disorder is used for function, as well as provide links to PubMed abstracts and major protein databases.

AVAILABILITY

www.disprot.org

摘要

未标注

蛋白质无序数据库(DisProt)是一个经过整理的数据库,它提供了关于在假定的天然条件下整体或部分缺乏固定三维(3D)结构的蛋白质的结构和功能信息。基于内在无序是蛋白质的一种重要结构类别的核心前提,并且为了满足对此日益增长的兴趣,DisProt旨在成为无序相关信息的核心存储库。对于每个无序蛋白质,数据库包括蛋白质名称、各种别名、登录号、氨基酸序列、无序区域的位置以及用于结构(无序)表征的方法。如果适用,大多数条目还列出每个无序区域的生物学功能、每个无序区域如何用于功能,以及提供指向PubMed摘要和主要蛋白质数据库的链接。

可用性

www.disprot.org

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